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LDHB / Lactate Dehydrogenase B

lactate dehydrogenase B

LDHB / Lactate Dehydrogenase B encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: lactate dehydrogenase B
Synonyms: LDHB, LDH heart subunit, Lactate dehydrogenase H chain, Lactate dehydrogenase B, LDH-B, TRG-5, LDH-H, LDHBD
Target Sequences: NM_002300 NP_002291.1 P07195

Publications (3)

1
M-LDH serves as a sarcolemmal K(ATP) channel subunit essential for cell protection against ischemia. Crawford RM, Budas GR, Jovanovi S, Ranki HJ, Wilson TJ, Davies AM, Jovanovi A. The EMBO journal. 2002 21:3936-48. [PubMed:12145195] [PMC:PMC126135]
2
Lactate dehydrogenase-5 (LDH-5) overexpression in non-small-cell lung cancer tissues is linked to tumour hypoxia, angiogenic factor production and poor prognosis. Koukourakis MI, Giatromanolaki A, Sivridis E, Bougioukas G, Didilis V, Gatter KC, Harris AL. British journal of cancer. 2003 89:877-85. [PubMed:12942121] [PMC:PMC2394471]
3
Small and big Hodgkin-Reed-Sternberg cells of Hodgkin lymphoma cell lines L-428 and L-1236 lack consistent differences in gene expression profiles and are capable to reconstitute each other. Rengstl B, Kim S, Döring C, Weiser C, Bein J, Bankov K, Herling M, Newrzela S, Hansmann ML, Hartmann S. PloS one. 2017 12:e0177378. (ICC, WB, ELISA; Human) [Full Text Article] [PubMed:28505189] Related Antibodies: LS-B4366.

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Antibodies (61)
Primary (61)
LDHB / Lactate Dehydrogenase B (61)
Human (61)
Mouse (32)
Rat (31)
Chicken (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Horse (1)
Monkey (4)
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IHC (12)
IHC-P (9)
WB (61)
ELISA (7)
ICC (11)
IF (3)
IP (10)
Peptide-ELISA (3)
rabbit (38)
mouse (21)
goat (2)
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IHCPlus (4)
IgG (29)
IgG1,k (1)
IgG2a (2)
IgG2a,k (1)
monoclonal mc (21)
polyclonal pc (40)
2H6 (1)
AT14D7 (1)
APC (5)
APC Conjugated (5)
Biotin Conjugated (6)
Cy3 Conjugated (5)
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FITC Conjugated (7)
HRP Conjugated (6)
PE Conjugated (5)
Unconjugated (22)
aa1-334 (41)
C-Terminus (4)
aa15-25 (1)
aa284-334 (1)
aa297-310 (1)
No (60)
Yes (1)
LDHB / Lactate Dehydrogenase B Antibody - Anti-LDHB antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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LDHB / Lactate Dehydrogenase B Mouse anti-Human Monoclonal (2H6) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
LDHB / Lactate Dehydrogenase B Antibody - Anti-LDHB / LDH-B antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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LDHB / Lactate Dehydrogenase B Goat anti-Human Polyclonal (aa15-25) Antibody
Horse, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
LDHB / Lactate Dehydrogenase B Antibody - Anti-LDHB antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
LDHB / Lactate Dehydrogenase B Antibody - Anti-LDHB antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Chicken, Rabbit, Dog, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
LDHB / Lactate Dehydrogenase B Antibody - Anti-LDHB antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Chicken, Rabbit, Dog, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
LDHB / Lactate Dehydrogenase B Antibody - Anti-LDHB antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Chicken, Rabbit, Dog, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
LDHB / Lactate Dehydrogenase B Antibody - Western Blot; Sample: Recombinant LDHB, Human.
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal (aa1-334) Antibody
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
LDHB / Lactate Dehydrogenase B Antibody - Western Blot; Sample: Recombinant LDHB, Human.
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal (aa1-334) (FITC) Antibody
Mouse, Rat, Human
WB
FITC Conjugated
100 µl/$341; 200 µl/$397; 500 µl/$583; 1 ml/$715; 2 ml/$953; 5 ml/$1,628
LDHB / Lactate Dehydrogenase B Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LDHB / Lactate Dehydrogenase B Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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LDHB / Lactate Dehydrogenase B Goat anti-Human Polyclonal (aa297-310) Antibody
Mouse, Rat, Pig, Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
LDHB / Lactate Dehydrogenase B Antibody - LDHB was detected in paraffin-embedded sections of mouse brain tissues using rabbit anti- LDHB Antigen Affinity purified polyclonal antibody
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
LDHB / Lactate Dehydrogenase B Antibody - ICC/IF analysis of LDHB in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human LDHB antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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LDHB / Lactate Dehydrogenase B Mouse anti-Human Monoclonal (AT14D7) Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
LDHB / Lactate Dehydrogenase B Antibody - Western blot of recombinant LDHB / LDH-B.
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LDHB / Lactate Dehydrogenase B Mouse anti-Human Monoclonal (aa1-334) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$492; 1 ml/$563; 2 ml/$758; 5 ml/$1,233
LDHB / Lactate Dehydrogenase B Antibody - Western blot of recombinant LDHB / LDH-B.
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LDHB / Lactate Dehydrogenase B Mouse anti-Human Monoclonal (aa1-334) (HRP) Antibody
Human
ICC, IP, WB
HRP Conjugated
100 µl/$339; 200 µl/$394; 500 µl/$577; 1 ml/$705; 2 ml/$942; 5 ml/$1,603
LDHB / Lactate Dehydrogenase B Antibody - Western blot of recombinant LDHB / LDH-B.
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LDHB / Lactate Dehydrogenase B Mouse anti-Human Monoclonal (aa1-334) (Biotin) Antibody
Human
ICC, IP, WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$520; 1 ml/$598; 2 ml/$828; 5 ml/$1,356
LDHB / Lactate Dehydrogenase B Antibody - Western blot of recombinant LDHB / LDH-B.
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LDHB / Lactate Dehydrogenase B Mouse anti-Human Monoclonal (aa1-334) (FITC) Antibody
Human
ICC, IP, WB
FITC Conjugated
100 µl/$348; 200 µl/$408; 500 µl/$608; 1 ml/$758; 2 ml/$996; 5 ml/$1,725
LDHB / Lactate Dehydrogenase B Antibody - Western blot of recombinant LDHB / LDH-B.
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LDHB / Lactate Dehydrogenase B Mouse anti-Human Monoclonal (aa1-334) (Cy3) Antibody
Human
ICC, IP, WB
Cy3 Conjugated
100 µl/$407; 200 µl/$492; 500 µl/$853; 1 ml/$1,013; 2 ml/$1,315; 5 ml/$2,465
LDHB / Lactate Dehydrogenase B Antibody - Western blot of recombinant LDHB / LDH-B.
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LDHB / Lactate Dehydrogenase B Mouse anti-Human Monoclonal (aa1-334) (PE) Antibody
Human
ICC, IP, WB
PE Conjugated
100 µl/$407; 200 µl/$492; 500 µl/$853; 1 ml/$1,013; 2 ml/$1,315; 5 ml/$2,465
LDHB / Lactate Dehydrogenase B Antibody - Western blot of recombinant LDHB / LDH-B.
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LDHB / Lactate Dehydrogenase B Mouse anti-Human Monoclonal (aa1-334) (APC) Antibody
Human
ICC, IP, WB
APC Conjugated
100 µl/$407; 200 µl/$492; 500 µl/$853; 1 ml/$1,013; 2 ml/$1,315; 5 ml/$2,465
LDHB / Lactate Dehydrogenase B Antibody - Western blot of recombinant LDHB / LDH-B.
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LDHB / Lactate Dehydrogenase B Mouse anti-Human Monoclonal (aa1-334) (APC, Cy7) Antibody
Human
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$506; 200 µl/$651; 500 µl/$1,156; 1 ml/$1,409; 2 ml/$1,972; 5 ml/$3,697
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
LDHB / Lactate Dehydrogenase B Antibody - Immunohistochemistry of paraffin-embedded mouse stomach tissue.
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
LDHB / Lactate Dehydrogenase B Antibody - IHC testing of FFPE human tonsil with LDHB antibody at 1ug/ml. HIER: steam section in pH6 citrate buffer for 20 min.
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LDHB / Lactate Dehydrogenase B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).