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LDHA / LDH1
Lactate Dehydrogenase A
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.
| Gene Name: | Lactate Dehydrogenase A |
| Synonyms: | LDHA, LDH muscle subunit, LDH1, Lactate dehydrogenase M, LDH-M, GSD11, Lactate dehydrogenase A, LDH-A, LDHM, PIG19, Proliferation-inducing gene 19 |
| Target Sequences: | NM_005566 NP_005557.1 P00338 |
Publications (2)
1
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Le A, Cooper CR, Gouw AM, Dinavahi R, Maitra A, Deck LM, Royer RE, Vander Jagt DL, Semenza GL, Dang CV. Proceedings of the National Academy of Sciences of the United States of America. 2010 107:2037-42. (WB)
[PubMed:20133848]
[PMC:PMC2836706]
2
Postpartum supplementation with fermented ammoniated condensed whey altered nutrient partitioning to support hepatic metabolism. R Caputo Oliveira, S J Erb, R S Pralle, H T Holdorf, C R Seely, H M White. The Breast : official journal of the European Society of Mastology. 2020 Aug;;103:7055-7067. [Full Text Article]
[PubMed:32534927]
Related Antibodies: LS-C143436.
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LDHA / LDH1 Rabbit anti-Human Polyclonal (aa280-332) Antibody
Mouse, Bovine, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
LDHA / LDH1 Rabbit anti-Human Polyclonal (aa280-332) (Biotin) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
LDHA / LDH1 Rabbit anti-Human Polyclonal (aa280-332) (DY650) Antibody
Bovine, Human
ICC, IF, IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
LDHA / LDH1 Rabbit anti-Human Polyclonal (aa280-332) (DY488) Antibody
Bovine, Human
ICC, IF, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
LDHA / LDH1 Rabbit anti-Human Polyclonal (aa280-332) (DY550) Antibody
Bovine, Human
ICC, IF, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
LDHA / LDH1 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$460
LDHA / LDH1 Goat anti-Rabbit Polyclonal (Lyophilized) (HRP) Antibody
Rabbit
ELISA, IF, IHC, IP, WB
HRP Conjugated, Lyophilized
100 µg/$552
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
Sandwich CLIA
12 x 8-Well Microstrips
Human
0.16 - 10 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Sandwich
96-Well Strip Plate
Chicken
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$565
Competitive EIA
96-Well Strip Plate
Mouse
0.156 - 10 mU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$968
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
Sandwich
96-Well Microplate
Pig
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$565
Sandwich
96-Well Microplate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
LDHA / LDH1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$440
LDHA / LDH1 Mouse anti-Human Monoclonal (OTI2D11) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$434
Sandwich
96-Well Strip Plate
Rat
39 - 2500 mU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$968
LDHA / LDH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
LDHA / LDH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC-P, IP, WB
Unconjugated
50 µg/$460
LDHA / LDH1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
LDHA / LDH1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
LDHA / LDH1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
LDHA / LDH1 Rabbit anti-Human Polyclonal (aa182-231) Antibody
Human
WB
Unconjugated
100 µl/$424
LDHA / LDH1 Rabbit anti-Human Polyclonal (aa204-232) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
LDHA / LDH1 Rabbit anti-Human Polyclonal (aa204-232) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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