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Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Gene Name: | linker for activation of T cells family, member 2 |
Synonyms: | LAT2, HSPC046, Non-T-cell activation linker, NTAL, LAB, WBSCR15, WBS15, WBSCR5, WSCR5 |
Target Sequences: | NM_022040 NP_115853.2 Q9GZY6 |
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