LAT

linker for activation of T cells

Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

LAT (7)

Publications

No (7)

Tag

GST (1)

His (1)

His-T7 (3)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human LAT Protein (Recombinant His) - LS-G1458

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261; 20 µg/$298; 100 µg/$454; 500 µg/$1,177

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Human LAT Protein (Recombinant GST) (Full Length) - LS-G33237

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

51.37 kDa

Price:

10 µg/$479; 25 µg/$670

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Human LAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80510

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.8 kDa

Price:

20 µg/$150

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LAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121616

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.8 kDa

Price:

100 µg/$494

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Human LAT Protein (Recombinant His-T7) (aa25-221) - LS-G11900

Source:

E. coli

Tag:

His-T7

Molecular Weight:

24.9 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Mouse LAT Protein (Recombinant His-T7) (aa30-237) - LS-G11902

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.0 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Rat LAT Protein (Recombinant His-T7) (aa33-227) - LS-G11904

Source:

E. coli

Tag:

His-T7

Molecular Weight:

24.7 kDa

Price:

50 µg/$512; 10 µg/$292; 200 µg/$1,018; 100 µg/$817; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359

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