LAT

linker for activation of T cells

Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

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Products

Antibodies (88)

ELISA Kits (20)

Proteins (7)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (3)

Over-Expression Lysate (2)

Primary (88)

Recombinant (5)

Sandwich (12)

Sandwich CLIA (2)

Target

LAT (115)

Reactivity

Human (88)

Mouse (55)

Rat (41)

Chicken (1)

Guinea pig (1)

Horse (1)

Monkey (3)

Porcine (1)

Rabbit (1)

Sheep (1)

Application

IHC (8)

IHC-P (5)

WB (84)

Flo (3)

ELISA (18)

IF (1)

IP (19)

Peptide-ELISA (9)

Host

rabbit (74)

mouse (12)

goat (1)

sheep (1)

Product Group

IHCPlus (1)

PathPlus Cancer (1)

Isotype

IgG (44)

IgG1 (5)

IgG1,k (2)

Clonality

monoclonal mc (12)

polyclonal pc (76)

Clone

3B11-1D5 (1)

LAT-01 (4)

LAT1111 (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (5)

96-Well Strip Plate (13)

APC (3)

APC Conjugated (5)

Biotin Conjugated (5)

Concentrated (1)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (5)

Preservative Free (1)

Unconjugated (57)

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Epitope

aa25-221 (8)

aa30-237 (8)

aa33-227 (8)

pTyr171 (4)

pTyr191 (4)

140-220 aa (2)

160-240 aa (2)

C-Terminus (2)

Cytoplasmic Domain (2)

aa31-233 (2)

pTyr255 (2)

60-140 aa (1)

Asp156 (1)

Leu185 (1)

N-Terminus (1)

Tyr191/Tyr220 (1)

aa107-156 (1)

aa171-220 (1)

aa191-240 (1)

aa201-262 (1)

aa258-269 (1)

aa28-233 (1)

aa30-113 (1)

aa70-120 (1)

aa86-135 (1)

p161 (1)

p171 (1)

p191 (1)

p255 (1)

pTyr132 (1)

pTyr220 (1)

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Publications

No (115)

Sample Type

Adherent Cell Cultures (3)

Cell Lysates (2)

Plasma (6)

Serum (6)

Tissue Homogenates (4)

Tag

GST (1)

His (1)

His-T7 (3)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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IHC-plus™ LAT Antibody (aa70-120) LS-B8007

(4.0) Rating

Antibody:

LAT Rabbit anti-Human Polyclonal (aa70-120) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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PathPlus™ LAT Antibody (Cytoplasmic Domain, clone LAT1111) LS-B2004

Cancer

(5.0) Rating

Antibody:

LAT Mouse anti-Human Monoclonal (Cytoplasmic Domain) (LAT1111) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

LAT Antibody (aa31-233) LS-C8427

Antibody:

LAT Rabbit anti-Human Polyclonal (aa31-233) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µg/$483; 400 µg/$832

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LAT Antibody (FITC) LS-C537449

Antibody:

LAT Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

FITC Conjugated

Price:

100 µl/$1,027

• Unconjugated
• FITC

• Unconjugated
• FITC

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Human LAT Protein (Recombinant His) - LS-G1458

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261; 20 µg/$298; 100 µg/$454; 500 µg/$1,177

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LAT Antibody (N-Terminus) LS-C83967

Antibody:

LAT Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$556

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LAT Antibody (phospho-Tyr191) LS-C821860

Antibody:

LAT Rabbit anti-Human Polyclonal (pTyr191) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

LAT Antibody (aa258-269) LS-C20174

Antibody:

LAT Goat anti-Human Polyclonal (aa258-269) Antibody

Reactivity:

Horse, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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LAT Antibody (clone 3B11-1D5) LS-C133721

Antibody:

LAT Mouse anti-Human Monoclonal (3B11-1D5) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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LAT Antibody (phospho-Tyr191) LS-C199190

Antibody:

LAT Rabbit anti-Human Polyclonal (pTyr191) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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LAT Antibody (160-240 aa) LS-C381248

Antibody:

LAT Rabbit anti-Human Polyclonal (160-240 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

LAT Antibody (Cytoplasmic Domain, clone LAT-01) LS-C46010

Antibody:

LAT Mouse anti-Human Monoclonal (Cytoplasmic Domain) (LAT-01) Antibody

Reactivity:

Human

Applications:

Flo, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$323

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LAT Antibody (clone LAT-01) LS-C758394

Antibody:

LAT Mouse anti-Human Monoclonal (LAT-01) Antibody

Reactivity:

Human

Applications:

Flo, IP, WB

Format:

Unconjugated

Price:

100 µg/$447

Select

LAT Antibody LS-C806760

Antibody:

LAT Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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LAT Antibody LS-C334193

Antibody:

LAT Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

LAT Antibody (phospho-Tyr220) LS-C291505

Antibody:

LAT Rabbit anti-Human Polyclonal (pTyr220) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

LAT Antibody (60-140 aa) LS-C384327

Antibody:

LAT Rabbit anti-Human Polyclonal (60-140 aa) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

LAT Antibody (140-220 aa) LS-C380922

Antibody:

LAT Rabbit anti-Human Polyclonal (140-220 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

LAT Antibody LS-C753038

Antibody:

LAT Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

LAT Antibody LS-C814166

Antibody:

LAT Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

LAT Antibody (140-220 aa) LS-C384332

Antibody:

LAT Rabbit anti-Human Polyclonal (140-220 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

LAT Antibody (160-240 aa) LS-C384333

Antibody:

LAT Rabbit anti-Human Polyclonal (160-240 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

LAT Antibody (aa31-233) LS-C189719

Antibody:

LAT Mouse anti-Human Monoclonal (aa31-233) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µg/$587

Select

LAT Antibody (clone LAT-01, Concentrated) LS-C202268

Antibody:

LAT Mouse anti-Human Monoclonal (Concentrated) (LAT-01) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated, Concentrated

Price:

0.1 mg/$508

Select

LAT Antibody (p161) LS-C825483

Antibody:

LAT Rabbit anti-Human Polyclonal (p161) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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