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LAMP2 / CD107b
lysosomal-associated membrane protein 2
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
| Gene Name: | lysosomal-associated membrane protein 2 |
| Family/Subfamily: | Cancer |
| Synonyms: | LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2 |
| Target Sequences: | NM_013995 NP_054701.1 P13473 |
Publications (3)
1
A missense change in the ATG4D gene links aberrant autophagy to a neurodegenerative vacuolar storage disease. Kyöstilä K, Syrjä P, Jagannathan V, Chandrasekar G, Jokinen TS, Seppälä EH, Becker D, Drögemüller M, Dietschi E, Drögemüller C, Lang J, Steffen F, Rohdin C, Jäderlund KH, Lappalainen AK, Hahn K, Wohlsein P, Baumgärtner W, Henke D, Oevermann A, Kere J, Lohi H, Leeb T. PLoS genetics. 2015 11:e1005169. (IHC; Canine)
[Full Text Article]
[PubMed:25875846]
[PMC:PMC4398399]
2
Databases for technical aspects of immunohistochemistry. Furukawa S, Nagaike M, Ozaki K. Journal of toxicologic pathology. 2017 30:79-107. (IHC; Canine)
[Full Text Article]
[PubMed:28190929]
[PMC:PMC5293696]
3
Basal Autophagy Is Altered in Lagotto Romagnolo Dogs with an ATG4D Mutation. Pernilla Syrjä, Tahira Anwar, Tarja Jokinen, Kaisa Kyöstilä, Karin Hultin Jäderlund, Francesca Cozzi, Cecilia Rohdin, Kerstin Hahn, Peter Wohlsein, Wolfgang Baumgärtner, Diana Henke, Anna Oevermann, Antti Sukura, Tosso Leeb, Hannes Lohi, Eeva-Liisa Eskelinen. Veterinary pathology. 2017 Nov;54:953-963. [Full Text Article]
[PubMed:28583040]
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Antibodies
(156)
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(13)
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(9)
Type
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(3)
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(2)
Primary
(156)
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(11)
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(6)
Target
LAMP2 / CD107b
(178)
Reactivity
Human
(96)
Mouse
(63)
Rat
(19)
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(1)
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(3)
Hamster
(1)
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(1)
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(1)
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(14)
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(39)
IHC-Fr
(18)
IHC-P
(19)
WB
(107)
Flo
(39)
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(45)
ICC
(32)
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(24)
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(1)
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(34)
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(1)
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rabbit
(86)
mouse
(43)
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(27)
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(5)
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(1)
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(56)
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(40)
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(9)
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(3)
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(4)
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(1)
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monoclonal mc
(73)
polyclonal pc
(83)
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02
(1)
05
(2)
10
(1)
141
(3)
157CT16.6.6
(2)
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6A10H10
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8E2F2
(1)
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(12)
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(5)
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(14)
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(1)
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(1)
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(1)
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(5)
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(16)
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(5)
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(1)
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(5)
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(23)
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(12)
PE
(1)
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(15)
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(1)
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(4)
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(1)
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(1)
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(57)
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aa29-192
(18)
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(8)
aa193-375
(8)
aa295-410
(8)
aa196-225
(7)
aa385-410
(7)
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(2)
aa400-411
(1)
Publications
No
(178)
Sample Type
Cell Culture Supernatants
(1)
Cell Lysates
(1)
Plasma
(6)
Serum
(6)
Tissue Homogenates
(3)
Tag
6His, C-terminus
(2)
GST, N-terminus
(1)
His
(3)
His-GST
(2)
Myc-DDK (Flag)
(5)
Species
Human
(9)
Mouse
(2)
Rat
(1)
Source
293T Cells
(1)
E. coli
(4)
HEK 293 Cells
(4)
Human Cells
(2)
Mammalian Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(1)
Low Endotoxin Level
Low endotoxin level
(3)
LAMP2 / CD107b Rat anti-Mouse Monoclonal (FITC) Antibody
Mouse
Flo, IHC, IHC-Fr, IHC-P, IP
FITC Conjugated
250 µg/$515
LAMP2 / CD107b Mouse anti-Human Monoclonal Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
LAMP2 / CD107b Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-P
Unconjugated
50 µg/$460
LAMP2 / CD107b Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$958
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$798
LAMP2 / CD107b Mouse anti-Human Monoclonal (Azide-free) (H4B4) Antibody
Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated, Azide-free
50 µg/$460
LAMP2 / CD107b Rat anti-Mouse Monoclonal (M3/84) Antibody
Mouse
Flo, IHC, IHC-Fr, IHC-P, IP
Unconjugated
100 µg/$562; 250 µg/$755
LAMP2 / CD107b Mouse anti-Dog Monoclonal (AC17) Antibody
Dog
Flo, IF, IP, WB
Unconjugated
0.1 mg/$457
LAMP2 / CD107b Rat anti-Mouse Monoclonal (M3/84) Antibody
Mouse
Flo, IHC-Fr, IHC-P, IP, WB
Unconjugated
0.1 mg/$385
LAMP2 / CD107b Rat anti-Mouse Monoclonal (GL2A7) Antibody
Rabbit, Mouse, Human
ICC, IF, IP
Unconjugated
25 µg/$331; 100 µg/$425
LAMP2 / CD107b Rat anti-Mouse Monoclonal (FITC) (GL2A7) Antibody
Rabbit, Mouse
ICC, IF, IP
FITC Conjugated
100 µg/$456
LAMP2 / CD107b Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LAMP2 / CD107b Rat anti-Mouse Monoclonal Antibody
Mouse
Flo, IHC, IHC-Fr, IP
Unconjugated
500 µg/$521
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.94kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
LAMP2 / CD107b Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IHC-Fr
FITC Conjugated
100 Tests/$518
LAMP2 / CD107b Mouse anti-Human Monoclonal (H4B4) Antibody
Human
Flo, ICC, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 ml/$386
LAMP2 / CD107b Rabbit anti-Mouse Monoclonal (Preservative Free) (141) Antibody
Mouse
Flo
Unconjugated, Preservative Free
100 µl/$412
LAMP2 / CD107b Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$341
LAMP2 / CD107b Rabbit anti-Mouse Monoclonal (FITC) (141) Antibody
Mouse
Flo
FITC Conjugated
25 Tests/$263; 100 Tests/$323
LAMP2 / CD107b Rabbit anti-Mouse Monoclonal (PE) (141) Antibody
Mouse
Flo
PE Conjugated
25 Tests/$263; 100 Tests/$323
LAMP2 / CD107b Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$412
LAMP2 / CD107b Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
LAMP2 / CD107b Mouse anti-Human Monoclonal (6A10H10) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
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of 178
product results
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