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LAMA3 / Laminin Alpha 3

laminin, alpha 3

LAMA3 / Laminin Alpha 3 belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants.

Gene Name: laminin, alpha 3
Family/Subfamily: Laminin , not assigned-Laminin
Synonyms: LAMA3, BM600, Epiligrin 170 kDa subunit, E170, Kalinin-165kDa, Lama3a, Laminin Alpha 3, Laminin alpha-3 chain, Laminin-5 alpha 3 chain, Nicein-150kDa, Laminin, alpha 3, LOCS, Nicein 150kD subunit, BM600 150kD subunit, BM600-150kDa, Epiligrin, Epiligrin alpha 3 subunit, Epiligrin subunit alpha, Kalinin 165kD subunit, Kalinin subunit alpha, Laminin subunit alpha-3, Laminin-5 subunit alpha, Laminin-6 subunit alpha, Laminin-7 subunit alpha, LAMNA, Nicein subunit alpha
Target Sequences: NM_000227 NP_000218.3 Q16787

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
LAMA3 / Laminin Alpha 3 (5)
No (5)
6His, N-terminus (1)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
LAMA3 / Laminin Alpha 3 Protein - Recombinant Laminin Alpha 3 By SDS-PAGE
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E. coli
6His, N-terminus
28.6 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
LAMA3 / Laminin Alpha 3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
LAMA3 / Laminin Alpha 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
190.3 kDa
20 µg/$215
LAMA3 / Laminin Alpha 3 Protein
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E. coli
His, N-Terminal
32.9 kDa
50 µg/$419
LAMA3 / Laminin Alpha 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
190.3 kDa
100 µg/$710
Viewing 1-5 of 5 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).