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Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
Gene Name: | l(3)mbt-like 2 (Drosophila) |
Synonyms: | L3MBTL2, DJ756G23.3, H-l(3)mbt-l, H-l(3)mbt-like protein 2, L(3)mbt-like 2 (Drosophila), DKFZP761I141, L(3)mbt-like protein 2, L3MBT |
Target Sequences: | NM_031488 NP_113676.2 Q969R5 |
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