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KRT6A / CK6A / Cytokeratin 6A
keratin 6A
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
| Gene Name: | keratin 6A |
| Family/Subfamily: | Keratin , not assigned-Keratin |
| Synonyms: | KRT6A, Allergen Hom s 5, CK6A, CK-6D, CK6C, Cytokeratin 6C, Cytokeratin-6A, Cytokeratin-6D, CK-6A, Cytokeratin 6A, K6D, Keratin 6 isoform k6d, Keratin 6D, Keratin-6A, Type-II keratin Kb6, CK6D, Cytokeratin 6D, K6A, K6C, Keratin 6 isoform k6a, Keratin 6A, Keratin 6C, KRT6D |
| Target Sequences: | NM_005554 NP_005545.1 P02538 |
Publications (1)
1
Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells. Chang Liu, Tiffany Tate, Ekatherina Batourina, Steven T Truschel, Steven Potter, Mike Adam, Tina Xiang, Martin Picard, Maia Reiley, Kerry Schneider, Manuel Tamargo, Chao Lu, Xiao Chen, Jing He, Hyunwoo Kim, Cathy Lee Mendelsohn. Nature communications. 2019 Oct;10:4589. [Full Text Article]
[PubMed:31597917]
[PMC:PMC6785552]
Related Antibodies: LS-B12036.
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KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal (aa333-382) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal (aa333-382) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal (aa333-382) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal (aa333-382) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
Cancer
KRT6A / CK6A / Cytokeratin 6A Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
E. coli
His
64 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Mouse Polyclonal (aa212-240) Antibody
Mouse
WB
Unconjugated
400 µl/$393
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$341
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal (aa240-289) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal (aa240-289) (HRP) Antibody
Xenopus, Rat, Mouse, Guinea pig, Bat, Horse, Gibbon, Human, Monkey, Chimpanzee, Orangutan
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal (aa240-289) (Biotin) Antibody
Xenopus, Rat, Mouse, Guinea pig, Bat, Horse, Gibbon, Human, Monkey, Chimpanzee, Orangutan
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal (aa240-289) (FITC) Antibody
Xenopus, Rat, Mouse, Guinea pig, Bat, Horse, Gibbon, Human, Monkey, Chimpanzee, Orangutan
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Mouse Polyclonal (aa212-240) Antibody
Mouse
ELISA, WB
Unconjugated
200 µl/$734
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Mouse Polyclonal (aa212-240) (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
200 µl/$952
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Mouse Polyclonal (aa212-240) (APC) Antibody
Mouse
ELISA, WB
APC Conjugated
200 µl/$952
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Mouse Polyclonal (aa212-240) (Azide-free) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$341
KRT6A / CK6A / Cytokeratin 6A Rabbit anti-Human Polyclonal (aa135-164) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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