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KRT4 / CK4 / Cytokeratin 4

keratin 4

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Name:	keratin 4
Family/Subfamily:	Keratin , not assigned-Keratin
Synonyms:	KRT4, CK-4, CK4, Cytokeratin 4, Cytokeratin-4, K4, Keratin 4, Type-II keratin Kb4, CYK4, Keratin-4
Target Sequences:	X07695 CAA30534.1 P19013

Publications (1)

A case of primary combined neuroendocrine carcinoma with squamous cell carcinoma in the upper gingiva. Mochizuki Y, Omura K, Sakamoto K, Nakanishi S, Satoh K, Marukawa E, Yamaguchi A. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2010 109:e34-9. (IHC) [PubMed:20303044]

Human KRT4 / CK4 / Cytokeratin 4 (Sandwich ELISA) ELISA Kit - LS-F7256

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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