KPNA1 / Importin Alpha 5

karyopherin alpha 1 (importin alpha 5)

Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

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Products

Antibodies (46)

Proteins (6)

Type

Over-Expression Lysate (2)

Primary (46)

Recombinant (4)

Target

KPNA1 / Importin Alpha 5 (52)

Reactivity

Human (46)

Mouse (31)

Rat (13)

Bat (7)

Bovine (7)

Chicken (6)

Chimpanzee (6)

Dog (7)

Gibbon (6)

Guinea pig (6)

Hamster (8)

Horse (6)

Monkey (6)

Orangutan (6)

Pig (6)

Rabbit (6)

Zebrafish (3)

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Application

IHC (7)

IHC-P (2)

WB (42)

ELISA (14)

ICC (2)

IF (12)

IP (6)

Peptide-ELISA (2)

Host

rabbit (35)

mouse (9)

goat (1)

rat (1)

Product Group

IHCPlus (1)

Isotype

IgG (26)

IgG1 (7)

IgG1,k (1)

IgG2a (1)

Clonality

monoclonal mc (9)

polyclonal pc (37)

Clone

114-E12 (1)

2A4-1B5 (1)

2D9 (1)

Format

APC (1)

APC Conjugated (3)

Biotin Conjugated (6)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (3)

Unconjugated (20)

Epitope

aa239-506 (8)

N-Terminus (4)

aa74-123 (4)

aa2-14 (1)

Publications

No (52)

Tag

6His, N-terminus (2)

GST (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

Select

Human KPNA1 / Importin Alpha 5 Protein (Recombinant 6His, N-terminus) (aa239-506) - LS-G15528

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

33.3 kDa

Price:

10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142

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IHC-plus™ KPNA1 / Importin Alpha 5 Antibody (clone 2A4-1B5) LS-B6105

(4.0) Rating

Antibody:

KPNA1 / Importin Alpha 5 Mouse anti-Human Monoclonal (2A4-1B5) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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KPNA1 / Importin Alpha 5 Antibody LS-C115908

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, ICC, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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KPNA1 / Importin Alpha 5 Antibody (Biotin) LS-C318915

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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KPNA1 / Importin Alpha 5 Antibody LS-C755301

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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KPNA1 / Importin Alpha 5 Antibody (aa74-123, HRP) LS-C458941

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal (aa74-123) (HRP) Antibody

Reactivity:

Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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KPNA1 / Importin Alpha 5 Antibody LS-C331667

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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KPNA1 / Importin Alpha 5 Antibody (clone 114-E12) LS-C16999

Antibody:

KPNA1 / Importin Alpha 5 Mouse anti-Human Monoclonal (114-E12) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$786

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KPNA1 / Importin Alpha 5 Antibody (HRP) LS-C548459

Antibody:

KPNA1 / Importin Alpha 5 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$1,017

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KPNA1 / Importin Alpha 5 Antibody (Biotin) LS-C528358

Antibody:

KPNA1 / Importin Alpha 5 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$1,017

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KPNA1 / Importin Alpha 5 Antibody (FITC) LS-C538314

Antibody:

KPNA1 / Importin Alpha 5 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$1,017

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KPNA1 / Importin Alpha 5 Antibody (APC) LS-C518468

Antibody:

KPNA1 / Importin Alpha 5 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

APC Conjugated

Price:

100 µl/$1,017

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KPNA1 / Importin Alpha 5 Antibody (PE) LS-C656479

Antibody:

KPNA1 / Importin Alpha 5 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

PE Conjugated

Price:

100 µl/$1,017

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

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KPNA1 / Importin Alpha 5 Antibody LS-C767803

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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KPNA1 / Importin Alpha 5 Antibody LS-C748664

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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KPNA1 / Importin Alpha 5 Antibody (clone 2D9) LS-C179427

Antibody:

KPNA1 / Importin Alpha 5 Rat anti-Mouse Monoclonal (2D9) Antibody

Reactivity:

Mouse, Rat, Hamster, Human

Applications:

ICC, WB

Format:

Unconjugated

Price:

100 µg/$427

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KPNA1 / Importin Alpha 5 Antibody LS-C806233

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

KPNA1 / Importin Alpha 5 Antibody LS-C192816

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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KPNA1 / Importin Alpha 5 Antibody LS-C780374

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

KPNA1 / Importin Alpha 5 Antibody LS-C308690

Antibody:

KPNA1 / Importin Alpha 5 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

KPNA1 / Importin Alpha 5 Antibody LS-C746233

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$448

Select

KPNA1 / Importin Alpha 5 Antibody (aa2-14) LS-C55041

Antibody:

KPNA1 / Importin Alpha 5 Goat anti-Human Polyclonal (aa2-14) Antibody

Reactivity:

Dog, Bovine, Hamster, Bat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

KPNA1 / Importin Alpha 5 Antibody (aa239-506) LS-C294983

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal (aa239-506) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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KPNA1 / Importin Alpha 5 Antibody LS-C71259

Antibody:

KPNA1 / Importin Alpha 5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

Select

KPNA1 / Importin Alpha 5 Antibody LS-C310840

Antibody:

KPNA1 / Importin Alpha 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Viewing 1-25 of 52 product results

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