KNG1 / Kininogen / Bradykinin

kininogen 1

1 Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.

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Products

Proteins (16)

Type

Over-Expression Lysate (4)

Recombinant (12)

Target

KNG1 / Kininogen / Bradykinin (16)

Publications

No (16)

Tag

6His, C-terminus (2)

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (5)

His-T7, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (10)

Mouse (2)

Rat (2)

Source

293T Cells (2)

E. coli (4)

HEK 293 Cells (3)

Human Cells (3)

Mammalian Cells (1)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (4)

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Rat KNG1 / Kininogen / Bradykinin Protein (Recombinant His-T7, N-terminus) (Gln19-Arg380) - LS-G133574

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

43.9kDa

Price:

10 µg/$265; 50 µg/$347; 200 µg/$682; 100 µg/$545; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866

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Human KNG1 / Kininogen / Bradykinin Protein (Recombinant 6His, N-terminus) (aa390-639) - LS-G22642

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

31.9 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human KNG1 / Kininogen / Bradykinin Protein (Recombinant 6His, C-terminus) (Gln19-Ser427) - LS-G39026

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.89kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human KNG1 / Kininogen / Bradykinin Protein (Recombinant GST) (Full Length) - LS-G29134

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

74.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human KNG1 / Kininogen / Bradykinin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66147

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.7 kDa

Price:

20 µg/$1,107

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Human KNG1 / Kininogen / Bradykinin Protein (Recombinant GST, N-terminus) (aa322-427) - LS-G59077

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human KNG1 / Kininogen / Bradykinin Protein (Recombinant His) (Gln19-Ser644) - LS-G97640

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

71.3 kDa

Price:

50 µg/$854

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Mouse KNG1 / Kininogen / Bradykinin Protein (Recombinant His) (Glu21-Ser480) - LS-G98804

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

52.5 kDa

Price:

50 µg/$854

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KNG1 / Kininogen / Bradykinin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99204

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.7 kDa

Price:

100 µg/$494

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Human KNG1 / Kininogen / Bradykinin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77038

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.7 kDa

Price:

20 µg/$150

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Human KNG1 / Kininogen / Bradykinin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77040

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.3 kDa

Price:

20 µg/$150

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KNG1 / Kininogen / Bradykinin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129720

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.3 kDa

Price:

100 µg/$494

Select

Human KNG1 / Kininogen / Bradykinin Protein (Recombinant 6His, C-terminus) (Gln19-Ser427) - LS-G140513

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.9 kDa

Price:

10 µg/$317; 50 µg/$524

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Rat KNG1 / Kininogen / Bradykinin Protein (Recombinant His) (aa390-639) - LS-G22999

Source:

Yeast

Tag:

His

Molecular Weight:

29.7 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Mouse KNG1 / Kininogen / Bradykinin Protein (Recombinant His) (aa22-379) - LS-G13578

Source:

E. coli

Tag:

His

Molecular Weight:

41.0 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human KNG1 / Kininogen / Bradykinin Protein (Recombinant His) (aa390-644) - LS-G13582

Source:

E. coli

Tag:

His

Molecular Weight:

29.7 kDa

Price:

10 µg/$260; 50 µg/$335; 100 µg/$497; 200 µg/$622; 1 mg/$1,588; 500 µg/$1,185; 5 mg/$2,522; 2 mg/$1,760

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