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KMT2D / MLL2
lysine (K)-specific methyltransferase 2D
Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.
| Gene Name: | lysine (K)-specific methyltransferase 2D |
| Synonyms: | KMT2D, AAD10, ALL1-related protein, KABUK1, KMS, Lysine N-methyltransferase 2D, MLL2, Kabuki make-up syndrome, ALR, CAGL114, KMT2B, Lysine N-methyltransferase 2B, TNRC21 |
| Target Sequences: | NM_003482 NP_003473.3 O14686 |
Publications (1)
1
MLL histone methylases regulate expression of HDLR-SR-B1 in presence of estrogen and control plasma cholesterol in vivo. Ansari KI, Kasiri S, Hussain I, Bobzean SA, Perrotti LI, Mandal SS. Molecular and cellular endocrinology. 2013 27:92-105. (ELISA; Human)
[Full Text Article]
[PubMed:23192982]
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Antibodies
(11)
Type
Primary
(11)
Target
KMT2D / MLL2
(11)
Reactivity
Human
(11)
Application
IHC
(4)
IHC-P
(3)
WB
(2)
ELISA
(8)
Peptide-ELISA
(2)
Host
rabbit
(9)
mouse
(1)
goat
(1)
Product Group
IHCPlus
(2)
Isotype
IgG
(8)
IgG2a,k
(1)
Clonality
monoclonal mc
(1)
polyclonal pc
(10)
Clone
2E1
(1)
Format
APC Conjugated
(1)
Azide-free
(1)
Biotin Conjugated
(1)
FITC Conjugated
(1)
HRP Conjugated
(1)
PE Conjugated
(1)
Unconjugated
(6)
Epitope
C-Terminus
(6)
aa2-14
(2)
Publications
No
(11)
KMT2D / MLL2 Mouse anti-Human Monoclonal (2E1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
KMT2D / MLL2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$282; 200 µl/$350
KMT2D / MLL2 Goat anti-Human Polyclonal (aa2-14) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$375
KMT2D / MLL2 Rabbit anti-Human Polyclonal (aa2-14) Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KMT2D / MLL2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA
Unconjugated
200 µl/$734
KMT2D / MLL2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
200 µl/$952
KMT2D / MLL2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
ELISA
FITC Conjugated
200 µl/$952
KMT2D / MLL2 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody
Human
ELISA
PE Conjugated
200 µl/$952
KMT2D / MLL2 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody
Human
ELISA
APC Conjugated
200 µl/$952
KMT2D / MLL2 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody
Human
ELISA
HRP Conjugated, Azide-free
200 µl/$952
KMT2D / MLL2 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$357
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