KMO

kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.

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Products

Proteins (12)

Type

Over-Expression Lysate (2)

Recombinant (10)

Target

KMO (12)

Publications

No (12)

Tag

10His, N-terminus (1)

6His, N-terminus (1)

6His-SUMO, N-terminus (1)

DDK,C-terminus (1)

GST (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Myc-DDK (Flag), C-terminus (2)

Species

Human (9)

Rat (2)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (4)

Sf9 Cells (1)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (3)

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Human KMO Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G22998

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

57.8 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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KMO Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100100

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.6 kDa

Price:

100 µg/$710

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Human KMO Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87162

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.6 kDa

Price:

20 µg/$215

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Human KMO Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G137430

Source:

E. coli

Tag:

10His, N-terminus

Molecular Weight:

61.9 kDa

Price:

20 µg/$323; 1 mg/$1,355; 100 µg/$420

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Human KMO Protein (Recombinant Myc-DDK (Flag), C-terminus) - LS-G142192

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag), C-terminus

Molecular Weight:

61.3 kDa

Price:

20 µg/$1,107

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Human KMO Protein (Recombinant Myc-DDK (Flag), C-terminus) - LS-G142193

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag), C-terminus

Molecular Weight:

61.6 kDa

Price:

20 µg/$1,107

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Human KMO Protein (Recombinant DDK,C-terminus) - LS-G142385

Source:

Sf9 Cells

Tag:

DDK,C-terminus

Molecular Weight:

55.6 kDa

Price:

20 µg/$677

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Human KMO Protein (Recombinant His-SUMO) (Full Length) - LS-G20902

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

71.8 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human KMO Protein (Recombinant GST) (Full Length) - LS-G31215

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

70.51 kDa

Price:

2 µg/$439

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Rat KMO Protein (Recombinant His-T7) (aa1-282) - LS-G25918

Source:

E. coli

Tag:

His-T7

Molecular Weight:

35.4 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Rat KMO Protein (Recombinant 6His-SUMO, N-terminus) (aa1-384) - LS-G56367

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Human KMO Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70470

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.6 kDa

Price:

20 µg/$1,107

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