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KLK6 / Kallikrein 6

kallikrein-related peptidase 6

Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

Gene Name: kallikrein-related peptidase 6
Family/Subfamily: Protease , Serine S1
Synonyms: KLK6, Bssp, HK6, Kallikrein-related peptidase 6, Kallikrein 6 (neurosin, zyme), Neurosin, Protease, serine, 18, Protease M, PRSS9, Serine protease 9, Zyme, Serine protease 18, Kallikrein 6, Kallikrein-6, PRSS18, SP59
Target Sequences: NM_002774 NP_002765.1 Q92876

☰ Filters
Products
Proteins (19)
Over-Expression Lysate (6)
Recombinant (13)
KLK6 / Kallikrein 6 (19)
No (19)
6His, C-terminus (2)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
GST-His, N-terminus (1)
His, N-terminus (1)
His,C-terminus (1)
His-GST (2)
Myc-DDK (Flag) (9)
Human (13)
Mouse (1)
Rat (2)
293T Cells (3)
E. coli (5)
HEK 293 Cells (7)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (3)
KLK6 / Kallikrein 6 Protein - Recombinant Kallikrein 6 By SDS-PAGE
Select
E. coli
His-GST
55.8 kDa
10 µg/$288; 50 µg/$487; 200 µg/$972; 1 mg/$2,109; 5 mg/$3,403; 2 mg/$2,298
KLK6 / Kallikrein 6 Protein - 12.5% SDS-PAGE of human KLK6 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
53.3 kDa
10 µg/$479; 25 µg/$670
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.17kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
Select
293T Cells
Myc-DDK (Flag)
26.86 kDa
20 µg/$150
KLK6 / Kallikrein 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.86 kDa
20 µg/$150
KLK6 / Kallikrein 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.86 kDa
20 µg/$150
KLK6 / Kallikrein 6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
KLK6 / Kallikrein 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.86 kDa
100 µg/$494
KLK6 / Kallikrein 6 Protein - Purified recombinant protein KLK6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
25.1 kDa
20 µg/$1,107
KLK6 / Kallikrein 6 Protein - Purified recombinant protein KLK6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
25.1 kDa
20 µg/$1,107
KLK6 / Kallikrein 6 Protein - Purified recombinant protein KLK6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
14.9 kDa
20 µg/$1,107
KLK6 / Kallikrein 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.86 kDa
100 µg/$494
KLK6 / Kallikrein 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.86 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.2 kDa
10 µg/$344; 50 µg/$584
KLK6 / Kallikrein 6 Protein - Recombinant Rat KLK6 Protein (His Tag)-Elabscience
Select
E. coli
His, N-terminus
26.32 kDa
20 µg/$270; 100 µg/$390
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.6 kDa
50 µg/$854
KLK6 / Kallikrein 6 Protein
Select
E. coli
6His, N-terminus
27 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
KLK6 / Kallikrein 6 Protein - Recombinant Kallikrein 6 By SDS-PAGE
Select
E. coli
GST-His, N-terminus
57.9 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,921
KLK6 / Kallikrein 6 Protein - Recombinant Kallikrein 6 By SDS-PAGE
Select
E. coli
His-GST
57.1 kDa
10 µg/$287; 50 µg/$480; 100 µg/$767; 200 µg/$957; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278
Viewing 1-19 of 19 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).