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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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KLK3 / PSA

kallikrein-related peptidase 3

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Seum levels of KLK3 (also known as PSA) are useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Gene Name: kallikrein-related peptidase 3
Family/Subfamily: Protease , Serine S1
Synonyms: KLK3, APS, Gamma-seminoprotein, Kallikrein-3, Kallikrein-related peptidase 3, P-30 antigen, Prostate specific antigen, Prostate-specific antigen, PSA, Semenogelase, KLK2A1, Seminin
Target Sequences: NM_001648 NP_001639.1 P07288

Publications (1)

1
Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells. Morrissey C, Gallis B, Solazzi JW, Kim BJ, Gulati R, Vakar-Lopez F, Goodlett DR, Vessella RL, Sasaki T. Anti-cancer drugs. 2010 21:423-32. (WB) [PubMed:20130467] [PMC:PMC2953769]

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Products
ELISA Kits (27)
Cell-Based (1)
Custom (1)
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Sandwich CLIA (3)
KLK3 / PSA (27)
Human (14)
Mouse (4)
Rat (6)
Chicken (1)
Monkey (1)
Rabbit (1)
Product Group
DevKit DuoPlus (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (8)
96-Well Strip Plate (15)
Antibody Pair and Standard (1)
No (27)
Adherent Cell Cultures (1)
Cell Culture Supernatants (7)
Cell Lysates (4)
Plasma (22)
Serum (22)
Tissue Homogenates (9)
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Microplate
Human
10.24 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Microplate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$675
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.2 - 12.5 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
KLK3 / PSA ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Rat
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
KLK3 / PSA ELISA Kit
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Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Microplate
Human
312 - 20000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Microplate
Human
49.16 - 4800 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
KLK3 / PSA ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
938 - 60000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$534
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
KLK3 / PSA ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
KLK3 / PSA ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
KLK3 / PSA ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
KLK3 / PSA ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
0.4 - 250 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$925; 1000 Wells/$1,319
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$782
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Human
312 - 20000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
KLK3 / PSA ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
KLK3 / PSA ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
54.87 - 40000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$851
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).