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KLK3 / PSA

kallikrein-related peptidase 3

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Seum levels of KLK3 (also known as PSA) are useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Gene Name: kallikrein-related peptidase 3
Family/Subfamily: Protease , Serine S1
Synonyms: KLK3, APS, Gamma-seminoprotein, Kallikrein-3, Kallikrein-related peptidase 3, P-30 antigen, Prostate specific antigen, Prostate-specific antigen, PSA, Semenogelase, KLK2A1, Seminin
Target Sequences: NM_001648 NP_001639.1 P07288

Publications (1)

1
Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells. Morrissey C, Gallis B, Solazzi JW, Kim BJ, Gulati R, Vakar-Lopez F, Goodlett DR, Vessella RL, Sasaki T. Anti-cancer drugs. 2010 21:423-32. (WB) [PubMed:20130467] [PMC:PMC2953769]

☰ Filters
Antibodies (242)
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KLK3 / PSA (285)
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113 (1)
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KLK3 / PSA Antibody - Anti-KLK3 / PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (aa26-251) (5A11E2) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
KLK3 / PSA Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
KLK3 / PSA Antibody - Anti-PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Select
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (C3F12) Antibody
Human
ELISPOT, Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
KLK3 / PSA ELISA Kit
Select
Sandwich
96-Well Microplate
Human
10.24 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
KLK3 / PSA Protein - Recombinant Kallikrein 3 By SDS-PAGE
Select
E. coli
His
26.3 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
KLK3 / PSA ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
KLK3 / PSA ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
KLK3 / PSA ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$675
KLK3 / PSA Antibody - Immunohistochemistry of paraffin-embedded mouse kidney tissue.
Select
KLK3 / PSA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
KLK3 / PSA Antibody - Anti-PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Select
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (1A7) Antibody
Human
ELISPOT, Flo, ICC, IHC, IHC-Fr, IHC-P
Unconjugated
100 µg/$485
Select
KLK3 / PSA Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
1 mg/$392
KLK3 / PSA Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
KLK3 / PSA Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC-P, WB
Unconjugated
50 µl/$460
KLK3 / PSA Antibody - HKLK3 Antibody (C234) western blot of A549 cell line lysates (35 ug/lane). The HKLK3 antibody detected the HKLK3 protein (arrow).
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KLK3 / PSA Mouse anti-Human Monoclonal (aa220-250) Antibody
Human
WB
Unconjugated
0.1 ml/$393
Select
KLK3 / PSA Rabbit anti-Human Polyclonal (50-130 aa, Internal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KLK3 / PSA ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
KLK3 / PSA Antibody - Anti-PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Select
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (3E6) Antibody
Human
ELISPOT, Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
Select
KLK3 / PSA Mouse anti-Human Monoclonal (Biotin) (A67-B/E3) Antibody
Human
ELISA, IHC-P, WB
Biotin Conjugated
0.1 mg/$326
KLK3 / PSA Antibody - Anti-KLK3 / PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Cancer Pathology
Cancer
KLK3 / PSA Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, IRMA
Unconjugated
0.1 mg/$460
KLK3 / PSA Antibody - Anti-PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Select
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (2B7) Antibody
Human
ELISA, Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
Select
KLK3 / PSA Mouse anti-Human Monoclonal (214) Antibody
Human
ELISA
Unconjugated
1 mg/$712
KLK3 / PSA Antibody - Anti-KLK3 / PSA antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (AT1D10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
KLK3 / PSA Antibody - Prostate Specific Antigen PSA antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (A67-B/E3) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
KLK3 / PSA Antibody - Prostate Specific Antigen PSA antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (Azide-free, BSA-free) (A67-B/E3) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
KLK3 / PSA Antibody - Formalin-fixed, paraffin-embedded human prostate carcinoma stained with PSA antibody (KLK3/801 + KLK3/1248).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (KLK3/801 + KLK3/1248) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
KLK3 / PSA ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.2 - 12.5 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
Viewing 1-25 of 285 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).