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KLK2 / Kallikrein 2

kallikrein-related peptidase 2

KLK2 / Kallikrein 2 is a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.

Gene Name: kallikrein-related peptidase 2
Family/Subfamily: Protease , Serine S1
Synonyms: KLK2, Glandular kallikrein 2, Glandular kallikrein-1, HGK-1, Kallikrein 2, prostatic, Kallikrein-2, Kallikrein-related peptidase 2, KLK2A2, Tissue kallikrein-2
Target Sequences: NM_005551 NP_005542.1 P20151

Publications (1)

1
Trp(250) -hK2 is defective in intracellular trafficking and activates the unfolded protein response. Eun Ju Choi, Sei Mee Yoon, Suman Lee, Jinu Lee. Genes to cells : devoted to molecular & cellular mechanisms. 2015 June;20:512-20. [Full Text Article] [PubMed:25847286] Related Antibodies: LS-C55038.

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Serum (4)
Tissue Homogenates (4)
KLK2 / Kallikrein 2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$968
KLK2 / Kallikrein 2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Biological Fluids, Plasma, Serum, Tissue Homogenates
1 Plate/$669
KLK2 / Kallikrein 2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
KLK2 / Kallikrein 2 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
KLK2 / Kallikrein 2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).