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KLHL3

kelch-like family member 3

KLHL3 is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: kelch-like family member 3
Synonyms: KLHL3, Kelch-like 3 (Drosophila), KIAA1129, PHA2D, Kelch (Drosophila)-like 3, Kelch-like protein 3
Target Sequences: NM_017415 NP_059111.2 Q9UH77

☰ Filters
Antibodies (36)
Proteins (5)
Over-Expression Lysate (2)
Primary (36)
Recombinant (3)
KLHL3 (41)
Human (36)
Mouse (12)
Rat (9)
Bat (9)
Bovine (12)
Chicken (3)
Chimpanzee (12)
Dog (9)
Gibbon (6)
Guinea pig (12)
Hamster (3)
Horse (9)
Monkey (6)
Orangutan (12)
Pig (9)
Rabbit (6)
IHC (11)
IHC-P (6)
WB (31)
ELISA (13)
IF (4)
IP (1)
Peptide-ELISA (3)
rabbit (35)
mouse (1)
Product Group
IHCPlus (1)
IgG (27)
polyclonal pc (36)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (6)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (1)
Unconjugated (16)
aa207-234 (7)
C-Terminus (4)
N-Terminus (4)
aa149-198 (4)
aa71-120 (4)
10-90 aa, N-terminal (1)
aa10-59 (1)
aa14-63 (1)
No (41)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
KLHL3 Antibody - Anti-KLHL3 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KLHL3 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
KLHL3 Antibody - Anti-KLHL3 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KLHL3 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
KLHL3 Antibody - Anti-KLHL3 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KLHL3 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
KLHL3 Antibody - Anti-KLHL3 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KLHL3 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
KLHL3 Antibody - KLHL3 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The KLHL3 antibody detected the KLHL3 protein (arrow).
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KLHL3 Rabbit anti-Human Polyclonal (aa207-234) Antibody
Human
WB
Unconjugated
400 µl/$393
KLHL3 Antibody - Western blot analysis of extracts of various cell lines, using KLHL3 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
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KLHL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
KLHL3 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KLHL3 antibody.
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KLHL3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
KLHL3 Antibody - A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KLHL3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
Select
KLHL3 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KLHL3 Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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KLHL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KLHL3 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KLHL3 Antibody. The picture on the right is blocked with the synthesized peptide.
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KLHL3 Rabbit anti-Human Polyclonal (aa10-59) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Select
KLHL3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
KLHL3 Antibody - Western blot analysis of the lysates from COLO205 cells using KLHL3 antibody.
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KLHL3 Rabbit anti-Human Polyclonal (aa14-63) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
KLHL3 Antibody - Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution of 1:100
Select
KLHL3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
KLHL3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
KLHL3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
KLHL3 Rabbit anti-Human Polyclonal (aa207-234) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
KLHL3 Rabbit anti-Human Polyclonal (aa207-234) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
KLHL3 Rabbit anti-Human Polyclonal (aa207-234) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
KLHL3 Rabbit anti-Human Polyclonal (aa207-234) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
KLHL3 Rabbit anti-Human Polyclonal (aa207-234) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
KLHL3 Rabbit anti-Human Polyclonal (aa207-234) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
KLHL3 Antibody - KLHL3 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KLHL3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
KLHL3 Antibody - Western blot of Human Breast Tumor. KLHL3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KLHL3 Rabbit anti-Human Polyclonal (aa149-198) Antibody
Human
WB
Unconjugated
100 µl/$424
KLHL3 Antibody - Western blot analysis of extracts of various cell lines using KLHL3 Polyclonal Antibody at dilution of 1:3000.
Select
KLHL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Viewing 1-25 of 41 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).