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KLHDC8A encodes a kelch domain-containing protein which is upregulated in cancer. Upregulated expression of the encoded protein may provide an alternative pathway for tumors to maintain aggressiveness in the absence of epidermal growth factor receptor dependence. Alternative splicing results in multiple transcript variants.
Gene Name: | kelch domain containing 8A |
Synonyms: | KLHDC8A, Kelch domain containing 8A, S-delta-E1 |
Target Sequences: | NM_018203 NP_060673.1 Q8IYD2 |
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