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KLB / Beta Klotho
klotho beta
Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.
| Gene Name: | klotho beta |
| Synonyms: | KLB, BetaKlotho, Beta-klotho, BKL, Klotho beta, Klotho beta like, Klotho beta-like protein |
| Target Sequences: | AA010359 Q86Z14 Q86Z14 |
Publications (8)
1
Ileal Transposition Surgery Decreases Fat Mass and Improves Glucose Metabolism in Diabetic GK Rats: Possible Involvement of FGF21. Yan K, Chen W, Zhu H, Lin G, Pan H, Li N, Wang L, Yang H, Liu M, Gong F. Frontiers in physiology. 2018 March;9:191. (Human)
[Full Text Article]
[PubMed:29593555]
[PMC:PMC5854974]
Related Antibodies: LS-B3568.
2
Hypocaloric Diet Prevents the Decrease in FGF21 Elicited by High Phosphorus Intake. Pineda C, Rios R, Raya AI, Rodriguez M, Aguilera-Tejero E, Lopez I. Nutrients. 2018 October;10:pii E1496. [Full Text Article]
[PubMed:30322116]
[PMC:PMC6213303]
Related Antibodies: LS-B3568.
3
Mistranslation Drives Alterations in Protein Levels and the Effects of a Synonymous Variant at the Fibroblast Growth Factor 21 Locus. Ali Bayoumi, Asmaa Elsayed, Shuanglin Han, Salvatore Petta, Leon A Adams, Rocio Aller, Anis Khan, Carmelo García-Monzón, María Teresa Arias-Loste, Luca Miele, Olivier Latchoumanin, Shafi Alenizi, Rocio Gallego-Durán, Janett Fischer, Thomas Berg, Antonio Craxì, Mayada Metwally, Liang Qiao, Christopher Liddle, Hannele Yki-Järvinen, Elisabetta Bugianesi, Manuel Romero-Gomez, Jacob George, Mohammed Eslam. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2021 June;8:2004168. [Full Text Article]
[PubMed:34141520]
[PMC:PMC8188187]
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(4)
KLB / Beta Klotho Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
KLB / Beta Klotho Rabbit anti-Human Polyclonal (aa517-636) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
KLB / Beta Klotho Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581; 2 ml/$798; 5 ml/$1,296
KLB / Beta Klotho Mouse anti-Human Monoclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$325; 200 µl/$373; 500 µl/$536; 1 ml/$628; 2 ml/$860; 5 ml/$1,425
KLB / Beta Klotho Mouse anti-Human Monoclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$356; 200 µl/$418; 500 µl/$638; 1 ml/$798; 2 ml/$1,035; 5 ml/$1,813
KLB / Beta Klotho Mouse anti-Human Monoclonal (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$418; 200 µl/$507; 500 µl/$887; 1 ml/$1,051; 2 ml/$1,383; 5 ml/$2,591
E. coli
His, N-Terminal
15.1 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
Sandwich
96-Well Strip Plate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$901
KLB / Beta Klotho Rabbit anti-Human Polyclonal (aa517-636) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
KLB / Beta Klotho Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
KLB / Beta Klotho Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
KLB / Beta Klotho Rabbit anti-Mouse Polyclonal (aa846-965) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
KLB / Beta Klotho Rabbit anti-Mouse Polyclonal (aa846-965) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$870
KLB / Beta Klotho Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
KLB / Beta Klotho Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
KLB / Beta Klotho Rabbit anti-Mouse Polyclonal (aa380-506) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
KLB / Beta Klotho Rabbit anti-Mouse Polyclonal (aa380-506) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
KLB / Beta Klotho Rabbit anti-Mouse Polyclonal (aa380-506) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
KLB / Beta Klotho Rabbit anti-Mouse Polyclonal (aa380-506) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
KLB / Beta Klotho Rabbit anti-Mouse Polyclonal (aa380-506) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
KLB / Beta Klotho Rabbit anti-Mouse Polyclonal (aa380-506) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
KLB / Beta Klotho Rabbit anti-Mouse Polyclonal (aa380-506) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
KLB / Beta Klotho Rabbit anti-Mouse Polyclonal (aa380-506) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
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of 51
product results
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