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KISS1 / Kisspeptin / Metastin

KiSS-1 metastasis-suppressor

Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca2+ levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.

Gene Name: KiSS-1 metastasis-suppressor
Synonyms: KISS1, HH13, Metastasis-suppressor KiSS-1, Kisspeptin-1, Metastin, KiSS-1, KiSS-1 metastasis-suppressor
Target Sequences: NM_002256 NP_002247.3 Q15726

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Products
ELISA Kits (17)
Competitive EIA (4)
Development Kit (1)
Sandwich (12)
KISS1 / Kisspeptin / Metastin (17)
Human (6)
Mouse (4)
Rat (5)
Bovine (1)
Cow (1)
Product Group
DevKit DuoPlus (1)
96-Well Strip Plate (16)
Antibody Pair and Standard (1)
No (17)
Cell Culture Supernatants (1)
Cell Lysates (2)
Cell Supernatant (1)
Plasma (17)
Serum (17)
Tissue Homogenates (6)
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$730
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$748
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
24.69 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$598
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$968
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Cow
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$816
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
24.69 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$730
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
62.4 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
500 Wells/$1,276; 1000 Wells/$1,903
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Viewing 1-17 of 17 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).