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Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.
Gene Name: | kinesin heavy chain member 2A |
Synonyms: | KIF2A, KNS2, KIF2, Kinesin heavy chain member 2A, Kinesin heavy chain member 2, Kinesin, heavy chain, 2, Kinesin-like protein KIF2A, Kinesin-2 |
Target Sequences: | NM_004520 NP_004511.2 O00139 |
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