KEAP1

kelch-like ECH-associated protein 1

Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.

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Products

Proteins (16)

Type

Over-Expression Lysate (4)

Recombinant (12)

Target

KEAP1 (16)

Application

SDS-PAGE (2)

Publications

No (15)

Yes (1)

Tag

6His, N-terminus (2)

6His-SUMO, N-terminus (1)

GST (1)

GST-AVI (1)

His-GST (1)

His-GST, N-terminus (1)

His-GST-AVI, N-terminus (1)

His-S (1)

Myc-DDK (Flag) (6)

Species

Human (12)

Mouse (2)

Source

293T Cells (2)

Baculovirus (5)

E. coli (3)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (5)

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Human KEAP1 Protein (Recombinant 6His, N-terminus) (aa1-624) - LS-G57209

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human KEAP1 Protein (Recombinant 6His, N-terminus) (aa327-624) - LS-G26132

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

36.5 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human KEAP1 Protein (Recombinant His-GST-AVI, N-terminus) (Gln2-Cys624) - LS-G141248

Source:

Baculovirus

Tag:

His-GST-AVI, N-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human KEAP1/GST chimera consists of 875 amino acids and has a calculated molecular mass of 99.2 kDa. It migrates as an approximately 85 kDa band in SDS-PAGE under reducing conditions.

Price:

100 µg/$441

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Human KEAP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66144

(4.0) Rating

(1) Publication(s)

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.5 kDa

Price:

20 µg/$1,107

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Human KEAP1 Protein (Recombinant GST) (Full Length) - LS-G31817

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

94.38 kDa

Price:

10 µg/$479; 25 µg/$670

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Human KEAP1 Protein (Recombinant His-GST, N-terminus) (Gln2-Cys624) - LS-G47719

Source:

Baculovirus

Tag:

His-GST, N-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human KEAP1/GST chimera consists of 861 amino acids and has a calculated molecular mass of 97.5 kDa. The recombinant protein migrates as an approximately 109 kDa band in SDS-PAGE under reducing conditions.

Price:

100 µg/$441

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Human KEAP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66145

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.5 kDa

Price:

20 µg/$1,107

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Human KEAP1 Protein (Recombinant His-GST) (Gln2-Cys624) - LS-G97630

Source:

Baculovirus

Tag:

His-GST

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

97.5 kDa

Price:

100 µg/$721

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KEAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103029

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.5 kDa

Price:

100 µg/$494

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KEAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101067

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.5 kDa

Price:

100 µg/$494

Select

Human KEAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77021

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.5 kDa

Price:

20 µg/$150

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Human KEAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77022

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.5 kDa

Price:

20 µg/$150

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Mouse KEAP1 Protein (Recombinant His-S) (aa1-286) - LS-G26133

Source:

E. coli

Tag:

His-S

Molecular Weight:

36 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Mouse KEAP1 Protein (Recombinant 6His-SUMO, N-terminus) (aa1-624) - LS-G56363

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human KEAP1 Protein (Recombinant) (Gln2-Cys624) - LS-G98608

Source:

Baculovirus

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

69.7 kDa

Price:

100 µg/$721

Select

Human KEAP1 Protein (Recombinant GST-AVI) (Gln2-Cys624) - LS-G97631

Source:

Baculovirus

Tag:

GST-AVI

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

99.2 kDa

Price:

100 µg/$721

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