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Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
Gene Name: | potassium large conductance calcium-activated channel, subfamily M, beta member 2 |
Family/Subfamily: | Ion Channel , Potassium channel - calcium-activated |
Synonyms: | KCNMB2, BK beta 2, HKCNMB2, Hbeta2, Maxi K beta 2, HCG1646471, K(VCA)beta-2, MaxiK channel beta 2 subunit, SLO-BETA2, BK channel subunit beta-2, BKbeta2, HBETA3, Maxi K channel subunit beta-2, Slo-beta-2 |
Target Sequences: | NM_005832 NP_005823.1 Q9Y691 |
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