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KCNJ13 / KIR7.1

potassium inwardly-rectifying channel, subfamily J, member 13

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.

Gene Name: potassium inwardly-rectifying channel, subfamily J, member 13
Family/Subfamily: Ion Channel , Potassium channel - inward-rectifying
Synonyms: KCNJ13, KIR7.1, LCA16, SVD, KIR1.4
Target Sequences: AB013889 BAA28271.1 O60928

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).