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Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Seems to be involved in KCND2 trafficking to the cell surface.
Gene Name: | Kv channel interacting protein 1 |
Family/Subfamily: | Ion Channel , Potassium channel - interacting protein |
Synonyms: | KCNIP1, KCHIP1, Vesicle APC-binding protein, VABP |
Target Sequences: | NM_014592 NP_055407.1 Q9NZI2 |
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