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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms.
Gene Name: | potassium voltage-gated channel, subfamily H (eag-related), member 6 |
Family/Subfamily: | Ion Channel , Potassium channel - Eag-related |
Synonyms: | KCNH6, Eag related protein 2, Eag-related gene member 2, ERG-2, Eag-related protein 2, ERG2, HERG-2, HERG2, Kv11.2 |
Target Sequences: | NM_030779 NP_110406.1 Q9H252 |
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