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Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).
Gene Name: | aminoadipate aminotransferase |
Synonyms: | AADAT, 2-aminoadipate transaminase, KAT2, KAT/AadAT, KATII, Kynurenine aminotransferase II, Aminoadipate aminotransferase |
Target Sequences: | NM_016228 NP_057312.1 Q8N5Z0 |
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