KAT5 / TIP60

K(lysine) acetyltransferase 5

Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation. Relieves NR1D2-mediated inhibition of APOC3 expression by acetylating NR1D2.

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Products

Proteins (13)

Type

Over-Expression Lysate (6)

Recombinant (7)

Target

KAT5 / TIP60 (13)

Publications

No (13)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (9)

Species

Human (10)

Source

293T Cells (3)

E. coli (1)

HEK 293 Cells (6)

Sf21 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human KAT5 / TIP60 Protein (Recombinant GST) (Full Length) - LS-G32199

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

76.34 kDa

Price:

2 µg/$439

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Human KAT5 / TIP60 Protein (Recombinant GST, N-terminus) (aa437-546) - LS-G61547

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human KAT5 / TIP60 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64780

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.6 kDa

Price:

20 µg/$1,107

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Human KAT5 / TIP60 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64781

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.4 kDa

Price:

20 µg/$1,107

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Human KAT5 / TIP60 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64782

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.9 kDa

Price:

20 µg/$1,107

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KAT5 / TIP60 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104187

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.6 kDa

Price:

100 µg/$710

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KAT5 / TIP60 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104186

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.9 kDa

Price:

100 µg/$494

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KAT5 / TIP60 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100805

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.4 kDa

Price:

100 µg/$494

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Human KAT5 / TIP60 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74174

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.4 kDa

Price:

20 µg/$150

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Human KAT5 / TIP60 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74175

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.6 kDa

Price:

20 µg/$215

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Human KAT5 / TIP60 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74176

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.9 kDa

Price:

20 µg/$150

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Human KAT5 / TIP60 Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G3995

Source:

Sf21 Cells

Tag:

6His, N-terminus

Price:

2 µg/$351

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Human KAT5 / TIP60 Protein (Recombinant His) (aa3-513) - LS-G22734

Source:

E. coli

Tag:

His

Molecular Weight:

62.4 kD

Price:

20 µg/$323; 1 mg/$1,355; 100 µg/$420

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