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Junctophilin 2 / JPH2
junctophilin 2
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH2 is necessary for proper intracellular Ca2+ signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release. Contributes to the construction of skeletal muscle triad junctions.
| Gene Name: | junctophilin 2 |
| Synonyms: | JPH2, JP-2, JP2, Junctophilin 2, CMH17, Junctophilin type 2, Junctophilin-2 |
| Target Sequences: | NM_020433 NP_065166.2 Q9BR39 |
Publications (1)
1
Mechanical unloading reverses transverse tubule remodelling and normalizes local Ca(2+)-induced Ca(2+)release in a rodent model of heart failure. Ibrahim M, Navaratnarajah M, Siedlecka U, Rao C, Dias P, Moshkov AV, Gorelik J, Yacoub MH, Terracciano CM. European journal of heart failure. 2012 14:571-80. (WB; Rat)
[PubMed:22467752]
[PMC:PMC3359860]
Related Antibodies: LS-C82883.
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Antibodies
(31)
Type
Primary
(31)
Target
Junctophilin 2 / JPH2
(31)
Reactivity
Human
(30)
Mouse
(9)
Rat
(8)
Bat
(3)
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(6)
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(3)
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(6)
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(3)
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(6)
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(3)
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(3)
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Application
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(7)
IHC-P
(5)
WB
(29)
ELISA
(11)
IF
(4)
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(1)
Host
rabbit
(21)
mouse
(10)
Product Group
IHCPlus
(2)
Isotype
IgG
(15)
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(4)
IgG2a
(4)
IgG2b
(2)
Clonality
monoclonal mc
(10)
polyclonal pc
(21)
Clone
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(2)
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(2)
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(2)
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(2)
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(2)
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(1)
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(1)
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(3)
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(5)
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(3)
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(3)
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(1)
Unconjugated
(20)
Epitope
aa614-643
(7)
aa408-457
(4)
aa66-115
(4)
aa625-675
(1)
Publications
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(30)
Yes
(1)
Junctophilin 2 / JPH2 Rabbit anti-Mouse Polyclonal (aa66-115) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Junctophilin 2 / JPH2 Rabbit anti-Mouse Polyclonal (aa66-115) (HRP) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
Junctophilin 2 / JPH2 Rabbit anti-Mouse Polyclonal (aa66-115) (Biotin) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
Junctophilin 2 / JPH2 Rabbit anti-Mouse Polyclonal (aa66-115) (FITC) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$460
Junctophilin 2 / JPH2 Mouse anti-Human Monoclonal (OTI1F5) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
Junctophilin 2 / JPH2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1F5) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal (aa408-457) Antibody
Human
WB
Unconjugated
100 µl/$424
Junctophilin 2 / JPH2 Mouse anti-Human Monoclonal (OTI1A1) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
Junctophilin 2 / JPH2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A1) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$351
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal (aa614-643) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal (aa614-643) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal (aa614-643) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal (aa614-643) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal (aa614-643) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal (aa614-643) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$357
Junctophilin 2 / JPH2 Rabbit anti-Human Polyclonal (aa625-675) Antibody
Human
IP, WB
Unconjugated
10 µg/$295; 100 µg/$514
Junctophilin 2 / JPH2 Mouse anti-Human Monoclonal (OTI1E1) Antibody
Human
WB
Unconjugated
100 µl/$434
Junctophilin 2 / JPH2 Mouse anti-Human Monoclonal (OTI2E5) Antibody
Human
WB
Unconjugated
100 µl/$434
Junctophilin 2 / JPH2 Mouse anti-Human Monoclonal (Carrier-free) (OTI2E5) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
Junctophilin 2 / JPH2 Mouse anti-Human Monoclonal (OTI2D3) Antibody
Human
WB
Unconjugated
100 µl/$434
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of 31
product results
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