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JUN / c-Jun
jun proto-oncogene
c-Jun is a component of the transcription factor activator protein 1 (AP-1) that binds to and activates transcription at TRE/AP-1 elements. Phosphorylation of c-Jun at Ser 63/73, resulting in activation and c-Jun dependent transcription, occurs in response to extra or intracellular signals, including UV irradiation, growth factors and transforming oncoproteins.
| Gene Name: | jun proto-oncogene |
| Family/Subfamily: | Transcription factor , not assigned-Transcription factor |
| Synonyms: | JUN, Activator protein 1, AP-1, C-Jun, Jun proto-oncogene, p39, Jun oncogene, Proto-oncogene c-Jun, AP1, Enhancer-binding protein AP1, G0s7, Transcription factor AP-1, v-jun |
| Target Sequences: | NM_002228 NP_002219.1 P05412 |
Publications (3)
1
Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos. Liao G, Tao Q, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsieh JC, Wylie C, Heasman J, Kuan CY. Proceedings of the National Academy of Sciences of the United States of America. 2006 103:16313-8. (WB)
[PubMed:17060633]
[PMC:PMC1637579]
2
Clara cells protein, prolactin and transcription factors of protein NF-?B and c-Jun/AP-1 levels in rats inhaled to stainless steel welding dust and its soluble form. Halatek T, Stanislawska M, Swiercz R, Domeradzka-Gajda K, Kuras R, Wasowicz W. International Journal of Occupational Medicine and Environmental Health. 2018 October;31:613-632. [Full Text Article]
[PubMed:30283154]
3
HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy. Michael F Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L Messina, Jurgen C Becker, Dirk Schadendorf, Edward Seto, Vernon K Sondak, John M Koomen, Yian A Chen, Eric K Lau, Lixin Wan, Jonathan D Licht, Keiran S M Smalley. Cancer research. 2019 June;79:2947-2961. [Full Text Article]
[PubMed:30987999]
[PMC:PMC6548652]
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JUN / c-Jun
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(1)
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(1)
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(1)
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(1)
Publications
No
(299)
Neuroscience
JUN / c-Jun Rabbit anti-Human Polyclonal (aa210-259) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, Peptide-ELISA, WB
Unconjugated
50 µl/$460
JUN / c-Jun Rabbit anti-Human Polyclonal (pSer63) Antibody
Rabbit, Mouse, Sheep, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
JUN / c-Jun Mouse anti-Human Monoclonal (OTI3G2) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
JUN / c-Jun Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
JUN / c-Jun Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
ChrIP, Flo, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
JUN / c-Jun Mouse anti-Human Monoclonal (OTI2A9) Antibody
Mouse, Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
JUN / c-Jun Mouse anti-Human Monoclonal (5B1) Antibody
Mouse, Human, Monkey
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
JUN / c-Jun Rabbit anti-Human Polyclonal (pSer63) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
JUN / c-Jun Rabbit anti-Human Polyclonal (pThr239) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
JUN / c-Jun Rabbit anti-Human Polyclonal (pThr239) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
JUN / c-Jun Mouse anti-Human Monoclonal (OTI2D11) Antibody
Mouse, Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
JUN / c-Jun Rabbit anti-Human Polyclonal (pSer63) Antibody
Human
DB, IHC, IHC-P, WB
Unconjugated
400 µl/$393
JUN / c-Jun Rabbit anti-Human Polyclonal (aa201-250) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
JUN / c-Jun Rabbit anti-Human Polyclonal Antibody
Xenopus, Chicken, Zebrafish, Pig, Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Human, Monkey
IF, IHC, WB
Unconjugated
50 µg/$489
JUN / c-Jun Rabbit anti-Human Polyclonal (pTyr170) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$315
JUN / c-Jun Mouse anti-Human Monoclonal (5B1) Antibody
Mouse, Human, Non-Human Primate
Flo, ICC, IF, IHC, WB
Unconjugated
100 µl/$541
JUN / c-Jun Mouse anti-Human Monoclonal Antibody
Human, Monkey
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
JUN / c-Jun Rabbit anti-Human Polyclonal (pSer73) Antibody
Xenopus, Chicken, Zebrafish, Pig, Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Human, Monkey
IHC, WB
Unconjugated
50 µg/$489
JUN / c-Jun Rabbit anti-Human Polyclonal (pSer63) Antibody
IF, WB
Unconjugated
20 µl/$287; 100 µl/$431
JUN / c-Jun Mouse anti-Human Monoclonal (4H9) Antibody
Mouse, Human
ICC, IF, IHC, WB
Unconjugated
100 µl/$541
JUN / c-Jun Mouse anti-Human Monoclonal (4H9) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$459
JUN / c-Jun Mouse anti-Human Monoclonal (UMAB49) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, PMA, WB
Unconjugated
100 µl/$493
JUN / c-Jun Mouse anti-Human Monoclonal (Carrier-free) (UMAB49) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
JUN / c-Jun Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$321
JUN / c-Jun Rabbit anti-Human Polyclonal (pSer243) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
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