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JEAP / AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: | angiomotin like 1 |
Synonyms: | AMOTL1, Angiomotin like 1, Angiomotin-like protein 1, JEAP |
Target Sequences: | Q8IY63 Q8IY63 |
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