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JAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.
Gene Name: | Junctional Adhesion Molecule 2 |
Synonyms: | JAM2, C21orf43, JAM-B, JAMB, Junctional adhesion molecule B, JAM-2, JAM-IT/VE-JAM, PRO245, VEJAM, VE-JAM, CD322, CD322 antigen, Junctional adhesion molecule 2 |
Target Sequences: | NM_021219 NP_067042.1 P57087 |
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