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ITPKC is a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.
Gene Name: | inositol-trisphosphate 3-kinase C |
Family/Subfamily: | Non-protein Kinase , ITPK |
Synonyms: | ITPKC, InsP 3 kinase C, IP3-3KC, InsP 3-kinase C, IP3KC, IP3K C, IP3 3-kinase C |
Target Sequences: | AJ290975 CAC40815.1 Q96DU7 |
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