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The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
Gene Name: | inositol-trisphosphate 3-kinase B |
Family/Subfamily: | Non-protein Kinase , ITPK |
Synonyms: | ITPKB, IP3 3-kinase B, IP3K-B, IP3-3KB, IP3KB, InsP 3-kinase B, IP3K, IP3K B, PIG37 |
Target Sequences: | NM_002221 NP_002212.3 P27987 |
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