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ITM2C

integral membrane protein 2C

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.

Gene Name: integral membrane protein 2C
Synonyms: ITM2C, BRICHOS domain containing 2C, BRICD2C, Cerebral protein 14, E25C, E25, Integral membrane protein 2C, Integral membrane protein 3, HRPC.1050_D_4, ITM3, Transmembrane protein BRI3
Target Sequences: NM_030926 NP_112188.1 Q9NQX7

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Products
Proteins (8)
Over-Expression Lysate (6)
Recombinant (2)
ITM2C (8)
No (8)
GST, N-terminus + His, C-terminus (1)
Myc-DDK (Flag) (7)
Human (5)
293T Cells (3)
E. coli (1)
HEK 293 Cells (4)
ITM2C Protein - Purified recombinant protein ITM2C was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.8 kDa
20 µg/$1,107
ITM2C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
30 kDa
100 µg/$494
ITM2C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
24.8 kDa
20 µg/$150
ITM2C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.7 kDa
20 µg/$150
ITM2C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
30 kDa
20 µg/$150
ITM2C Protein
Select
E. coli
GST, N-terminus + His, C-terminus
53.7 kDa
50 µg/$419
ITM2C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
24.8 kDa
100 µg/$494
ITM2C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.7 kDa
100 µg/$494
Viewing 1-8 of 8 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).