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ITGA9 / Integrin Alpha 9 is an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.
Gene Name: | integrin, alpha 9 |
Family/Subfamily: | Integrin , not assigned-Integrin |
Synonyms: | ITGA9, Integrin alpha-9, Integrin alpha-RLC, ALPHA-RLC, Integrin Alpha 9, Integrin, alpha 9, ITGA4L, RLC |
Target Sequences: | NM_002207 NP_002198.2 Q13797 |
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