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ITGA7 / Integrin Alpha 7

integrin, alpha 7

ITGA7 encodes integrin alpha chain 7. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 7 undergoes post-translational cleavage within the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that binds to the extracellular matrix protein laminin-1. Alpha 7 beta 1 is the major integrin complex expressed in differentiated muscle cells. Splice variants of alpha 7 that differ in both the extracellular and cytoplasmic domains exist in the mouse; however, to date only a single human transcript type has been isolated: it contains extracellular and cytoplasmic domains corresponding to the mouse X2 and B variants, respectively. A unique extracellular splice variant has been identified in human, although it clearly represents a minor species and its biological significance is unclear.

Gene Name: integrin, alpha 7
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGA7, Alpha 7b integrin, Integrin alpha-7, Integrin alpha 7 chain, Integrin, alpha 7
Target Sequences: NM_002206 NP_002197.2 Q13683

Publications (3)

1
Maintaining bovine satellite cells stemness through p38 pathway. Ding S, Swennen GNM, Messmer T, Gagliardi M, Molin DGM, Li C, Zhou G, Post MJ. Scientific reports. 2018 July;8:10808. (Human) [Full Text Article] [PubMed:30018348] [PMC:PMC6050236] Related Antibodies: LS-C313325.
2
Integrins functioning in uterine endometrial stromal and epithelial cells in estrus. Hye Jin Park, Ji Eun Park, Hyun Lee, Seong Jae Kim, Jung Im Yun, Minseok Kim, Kyu Hyun Park, Seung Tae Lee. Reproduction (Cambridge, England). 2017 Mar;153:351-360. [Full Text Article] [PubMed:27998942] Related Antibodies: LS-C179570.
3
Laminin a2 controls mouse and human stem cell behaviour during midbrain dopaminergic neuron development. Maqsood Ahmed, Leandro N Marziali, Ernest Arenas, M Laura Feltri, Charles Ffrench-Constant. Development (Cambridge, England). 2019 Aug;146:dev172668. [Full Text Article] [PubMed:31371375] [PMC:PMC6737905]

☰ Filters
Products
Antibodies (24)
Primary (24)
ITGA7 / Integrin Alpha 7 (24)
Human (22)
Mouse (6)
Rat (3)
Monkey (1)
IHC (3)
IHC-P (2)
WB (16)
Flo (3)
ELISA (13)
ICC (1)
IF (1)
Peptide-ELISA (3)
rabbit (20)
mouse (4)
Product Group
IHCPlus (2)
IgG (15)
IgG1 (2)
IgG1,k (1)
IgG2a,k (1)
monoclonal mc (4)
polyclonal pc (20)
3C12 (3)
8G2 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (3)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (14)
aa229-257 (7)
910-990 aa, C-terminal (1)
C-Terminus (1)
aa1123-1139 (1)
aa1149-1181 (1)
aa247-279 (1)
aa940-989 (1)
light chain, Cleaved-Glu959 (1)
No (22)
Yes (2)
ITGA7 / Integrin Alpha 7 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ITGA7 / Integrin Alpha 7 Mouse anti-Mouse Monoclonal (3C12) Antibody
Mouse, Human
Flo, ICC, IHC, IHC-P
Unconjugated
50 µg/$460
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ITGA7 / Integrin Alpha 7 Mouse anti-Mouse Monoclonal (FITC) (3C12) Antibody
Mouse
Flo
FITC Conjugated
100 µl/$352
ITGA7 / Integrin Alpha 7 Antibody - WB of ITGA7 / Integrin Alpha 7 antibody. Lane 1: 293T Cell Lysate. Lane 2: A431 Cell Lysate. Lane 3: HELA Cell Lysate. Lane 4: JURKAT Cell Lysate. Lane 5: RAJI Cell Lysate.
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ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa1123-1139) Antibody
Mouse, Rat, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
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ITGA7 / Integrin Alpha 7 Mouse anti-Mouse Monoclonal (PE) (3C12) Antibody
Mouse
Flo
PE Conjugated
1 ml/$421
ITGA7 / Integrin Alpha 7 Antibody - All lanes : Anti-ITGA7 Antibody at 1:2000 dilution Lane 1: HeLa whole cell lysates Lane 2: Jurkat whole cell lysates Lane 3: Raji whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 129 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa1149-1181) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
ITGA7 / Integrin Alpha 7 Antibody - Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ITGA7 / Integrin Alpha 7 Mouse anti-Human Monoclonal (8G2) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ITGA7 / Integrin Alpha 7 Antibody - Immunofluorescence staining of Hela cells diluted at 1:233, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The Secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
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ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ITGA7 / Integrin Alpha 7 Antibody - Western blot of Cleaved-Integrin alpha7 LC (E959) antibody
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ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (910-990 aa, C-terminal) Antibody
Human, Monkey
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ITGA7 / Integrin Alpha 7 Antibody - Western blot analysis of extracts from COS-7 cells, treated with etoposide (25uM, 1hour), using ITGA7 (light chain, Cleaved-Glu959) antibody.
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ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (light chain, Cleaved-Glu959) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
ITGA7 / Integrin Alpha 7 Antibody - Western blot of extracts from COS7 cells, treated with etoposide 25 uM 1h, using ITGA7 (light chain, Cleaved-Glu959) Antibody. The lane on the right is treated with the synthesized peptide.
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ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa940-989) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ITGA7 / Integrin Alpha 7 Antibody - All lanes : Anti-ITGA7 Antibody at 1:2000 dilution Lane 1: HeLa whole cell lysates Lane 2: A431 whole cell lysates Lane 3: Jurkat whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 129 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa247-279) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) Antibody
Human
WB
Unconjugated
200 µl/$734
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ITGA7 / Integrin Alpha 7 Antibody - ITGA7 Antibody western blot of CEM cell line lysates (35 ug/lane). The ITGA7 antibody detected the ITGA7 protein (arrow).
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ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) Antibody
Human
WB
Unconjugated
400 µl/$393
ITGA7 / Integrin Alpha 7 Antibody - Western blot analysis of Integrin alpha 7 LC expression in HeLa LPS-treated (A); Raw264.7 UV-treated (B); PC12 UV-treated (C) whole cell lysates.
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ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
ITGA7 / Integrin Alpha 7 Antibody - Western blot analysis of extracts of U-87MG cells, using ITGA7 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).