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ITGA7 / Integrin Alpha 7
integrin, alpha 7
ITGA7 encodes integrin alpha chain 7. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 7 undergoes post-translational cleavage within the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that binds to the extracellular matrix protein laminin-1. Alpha 7 beta 1 is the major integrin complex expressed in differentiated muscle cells. Splice variants of alpha 7 that differ in both the extracellular and cytoplasmic domains exist in the mouse; however, to date only a single human transcript type has been isolated: it contains extracellular and cytoplasmic domains corresponding to the mouse X2 and B variants, respectively. A unique extracellular splice variant has been identified in human, although it clearly represents a minor species and its biological significance is unclear.
| Gene Name: | integrin, alpha 7 |
| Family/Subfamily: | Integrin , not assigned-Integrin |
| Synonyms: | ITGA7, Alpha 7b integrin, Integrin alpha-7, Integrin alpha 7 chain, Integrin, alpha 7 |
| Target Sequences: | NM_002206 NP_002197.2 Q13683 |
Publications (3)
1
Maintaining bovine satellite cells stemness through p38 pathway. Ding S, Swennen GNM, Messmer T, Gagliardi M, Molin DGM, Li C, Zhou G, Post MJ. Scientific reports. 2018 July;8:10808. (Human)
[Full Text Article]
[PubMed:30018348]
[PMC:PMC6050236]
Related Antibodies: LS-C313325.
2
Integrins functioning in uterine endometrial stromal and epithelial cells in estrus. Hye Jin Park, Ji Eun Park, Hyun Lee, Seong Jae Kim, Jung Im Yun, Minseok Kim, Kyu Hyun Park, Seung Tae Lee. Reproduction (Cambridge, England). 2017 Mar;153:351-360. [Full Text Article]
[PubMed:27998942]
Related Antibodies: LS-C179570.
3
Laminin a2 controls mouse and human stem cell behaviour during midbrain dopaminergic neuron development. Maqsood Ahmed, Leandro N Marziali, Ernest Arenas, M Laura Feltri, Charles Ffrench-Constant. Development (Cambridge, England). 2019 Aug;146:dev172668. [Full Text Article]
[PubMed:31371375]
[PMC:PMC6737905]
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(24)
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Primary
(24)
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Target
ITGA7 / Integrin Alpha 7
(25)
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Human
(22)
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(6)
Rat
(3)
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(1)
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(3)
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(2)
WB
(16)
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(3)
ELISA
(13)
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(1)
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(1)
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(3)
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rabbit
(20)
mouse
(4)
Product Group
IHCPlus
(2)
Isotype
IgG
(15)
IgG1
(2)
IgG1,k
(1)
IgG2a,k
(1)
Clonality
monoclonal mc
(4)
polyclonal pc
(20)
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(3)
8G2
(1)
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APC Conjugated
(1)
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(1)
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(2)
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(3)
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(2)
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(2)
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(14)
Epitope
aa229-257
(7)
910-990 aa, C-terminal
(1)
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(1)
aa1123-1139
(1)
aa1149-1181
(1)
aa247-279
(1)
aa940-989
(1)
light chain, Cleaved-Glu959
(1)
Publications
No
(23)
Yes
(2)
Tag
GST, N-terminus
(1)
Species
Human
(1)
Source
Wheat Germ Extract
(1)
ITGA7 / Integrin Alpha 7 Mouse anti-Mouse Monoclonal (3C12) Antibody
Mouse, Human
Flo, ICC, IHC, IHC-P
Unconjugated
50 µg/$460
ITGA7 / Integrin Alpha 7 Mouse anti-Mouse Monoclonal (FITC) (3C12) Antibody
Mouse
Flo
FITC Conjugated
100 µl/$352
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa1123-1139) Antibody
Mouse, Rat, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
ITGA7 / Integrin Alpha 7 Mouse anti-Mouse Monoclonal (PE) (3C12) Antibody
Mouse
Flo
PE Conjugated
1 ml/$421
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa1149-1181) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
ITGA7 / Integrin Alpha 7 Mouse anti-Human Monoclonal (8G2) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (910-990 aa, C-terminal) Antibody
Human, Monkey
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (light chain, Cleaved-Glu959) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa940-989) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa247-279) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) Antibody
Human
WB
Unconjugated
200 µl/$734
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (aa229-257) Antibody
Human
WB
Unconjugated
400 µl/$393
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
ITGA7 / Integrin Alpha 7 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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