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ITGA5/Integrin Alpha 5/CD49e

integrin, alpha 5 (fibronectin receptor, alpha polypeptide)

ITGA5/Integrin Alpha 5/CD49e belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes.

Gene Name: integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGA5, FNRA, Integrin alpha-5, Integrin Alpha 5, Integrin alpha-F, VLA-5, CD49e, CD49e antigen, VLA5A
Target Sequences: NM_002205 NP_002196.2 P08648

Publications (3)

1
Correction to: In vivo imaging of early stages of rheumatoid arthritis by a5ß1-integrin-targeted positron emission tomography. Notni J, Gassert FT, Steiger K, Sommer P, Weichert W, Rummeny EJ, Schwaiger M, Kessler H, Meier R, Kimm MA. EJNMMI research. 2019 December;9:107. [Full Text Article] [PubMed:31828445] [PMC:PMC6906272] Related Antibodies: LS-B6179.
2
Development of the Fibronectin-Mimetic Peptide KSSPHSRN(SG)5RGDSP as a Novel Radioprobe for Molecular Imaging of the Cancer Biomarker a5ß1 Integrin. Zhao-Hui Jin, Takako Furukawa, Katsushi Kumata, Lin Xie, Joji Yui, Hidekatsu Wakizaka, Yasuhisa Fujibayashi, Ming-Rong Zhang, Tsuneo Saga. Biological & pharmaceutical bulletin. 2015 August;38:1722-31. [Full Text Article] [PubMed:26277991]
3
Complementary, Selective PET Imaging of Integrin Subtypes a5ß1 and avß3 Using 68Ga-Aquibeprin and 68Ga-Avebetrin. Johannes Notni, Katja Steiger, Frauke Hoffmann, Dominik Reich, Tobias G Kapp, Florian Rechenmacher, Stefanie Neubauer, Horst Kessler, Hans-Jürgen Wester. The Breast : official journal of the European Society of Mastology. 2016 Mar;;57:460-6. [Full Text Article] [PubMed:26635338] Related Antibodies: LS-B6179.

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ITGA5/Integrin Alpha 5/CD49e ELISA Kit
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0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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1 Plate/$798
ITGA5/Integrin Alpha 5/CD49e ELISA Kit
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Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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1 Plate/$669
ITGA5/Integrin Alpha 5/CD49e ELISA Kit
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Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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1 Plate/$669
ITGA5/Integrin Alpha 5/CD49e ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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1 Plate/$579
ITGA5/Integrin Alpha 5/CD49e ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).