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ITGA2 / CD49b

integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

ITGA2 encodes integrin alpha chain 2. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing alpha integrin 2 combines with beta integrin 1 to form a collagen-binding integrin referred to as glycoprotein Ia/IIa when expressed on platelets, and very late (activation) antigen 2 ('VLA-2') when found on T-cells. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Gene Name: integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGA2, Alpha2 integrin, BR, CD49b antigen, CD49B, Integrin alpha2, Integrin Alpha 2, Integrin alpha-2, HPA-5, VLA-2, VLAA2, VLA-2 subunit alpha, Collagen receptor, GPIa, Platelet antigen Br, Platelet glycoprotein GPIa, VLA2 receptor, alpha-2 subunit
Target Sequences: NM_002203 CAA34894.1 P17301

Publications (1)

1
Alpha2beta1 integrin regulates lineage commitment in multipotent human colorectal cancer cells. Kirkland SC, Ying H. The Journal of biological chemistry. 2008 283:27612-9. [PubMed:18664572] [PMC:PMC2562061]

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Products
Antibodies (171)
Primary (171)
ITGA2 / CD49b (171)
Human (115)
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Rat (3)
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rabbit (74)
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No (171)
ITGA2 / CD49b Antibody - Anti-ITGA2 / CD49b antibody IHC of human thymus, medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ITGA2 / CD49b Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Dog, Pig, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ITGA2 / CD49b Antibody - Anti-ITGA2 / CD49b antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ITGA2 / CD49b Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
ITGA2 / CD49b Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using ITGA2 Polyclonal Antibody at dilution of 1:30.
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ITGA2 / CD49b Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ITGA2 / CD49b Antibody - ITGA2 Antibody western blot of WiDr cell line lysates (35 ug/lane). The ITGA2 antibody detected the ITGA2 protein (arrow).
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ITGA2 / CD49b Rabbit anti-Human Polyclonal (aa1152-1180) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
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ITGA2 / CD49b Mouse anti-Human Monoclonal (16B4) Antibody
Human
ELISA, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
25 µg/$281; 0.2 mg/$471
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ITGA2 / CD49b Hamster anti-Mouse Monoclonal (HMa2) Antibody
Mouse
ELISA, Flo, IF, IHC, IHC-Fr, IP
Unconjugated
500 µg/$973
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ITGA2 / CD49b Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC
FITC Conjugated
120 Tests/$626
ITGA2 / CD49b Antibody
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ITGA2 / CD49b Rat anti-Mouse Monoclonal (PerCP) (DX5) Antibody
Mouse
Flo
PerCP Conjugated
50 Tests/$241; 100 Tests/$256; 200 Tests/$292
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ITGA2 / CD49b Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IP, WB
Unconjugated
200 µg/$732
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ITGA2 / CD49b Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
HRP Conjugated
100 µl/$951
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ITGA2 / CD49b Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Biotin Conjugated
100 µl/$951
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ITGA2 / CD49b Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
FITC Conjugated
100 µl/$951
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ITGA2 / CD49b Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
PE Conjugated
100 µl/$951
ITGA2 / CD49b Antibody - Surface staining of human PHA-activated leukocytes with anti-human CD134 purified, GAM APC.
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ITGA2 / CD49b Mouse anti-Human Monoclonal (AK7) Antibody
Human, Non-Human Primates
ELISA, Flo, ICC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$302
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ITGA2 / CD49b Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, IP
Unconjugated
100 µg/$543
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ITGA2 / CD49b Mouse anti-Human Monoclonal (Low Endotoxin) (AK7) Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated, Low Endotoxin
0.5 mg/$671
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ITGA2 / CD49b Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IP
Unconjugated
200 µg/$732
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ITGA2 / CD49b Mouse anti-Human Monoclonal (31H4) Antibody
Human
ELISA, Flo, IP
Unconjugated
0.2 mg/$471
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ITGA2 / CD49b Rabbit anti-Cow Polyclonal (aa106-302) (FITC) Antibody
Bovine, Cow
ICC, IP, WB
FITC Conjugated
100 µl/$367; 200 µl/$433; 500 µl/$686; 1 ml/$846; 2 ml/$1,092; 5 ml/$1,951
ITGA2 / CD49b Antibody - Western blot of ITGA2 / CD49b antibody.
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ITGA2 / CD49b Rabbit anti-Mouse Polyclonal (aa212-370) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
ITGA2 / CD49b Antibody - Western blot of ITGA2 / CD49b antibody.
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ITGA2 / CD49b Rabbit anti-Mouse Polyclonal (aa212-370) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676
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ITGA2 / CD49b Mouse anti-Human Monoclonal (PE) Antibody
Human
IF
PE Conjugated
100 µl/$1,089
ITGA2 / CD49b Antibody
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ITGA2 / CD49b Rat anti-Mouse Monoclonal (PE, Cy5) (DX5) Antibody
Mouse
Flo
PE, Cy5 Conjugated
50 Tests/$241; 100 Tests/$256; 200 Tests/$292
ITGA2 / CD49b Antibody - ITGA2 / CD49b antibody Western Blot of HT1080.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ITGA2 / CD49b Rabbit anti-Human Polyclonal (aa899-948) Antibody
Human
WB
Unconjugated
100 µl/$424
ITGA2 / CD49b Antibody - Western blot of recombinant ITGA2 / CD49b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ITGA2 / CD49b Rabbit anti-Human Polyclonal (aa74-277) (APC) Antibody
Mouse, Pig, Human
WB
APC Conjugated
100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).