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ISG54 / IFIT2
interferon-induced protein with tetratricopeptide repeats 2
IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.
| Gene Name: | interferon-induced protein with tetratricopeptide repeats 2 |
| Synonyms: | IFIT2, Cig42, GARG-39, IFI-54, IFI-54K, IFIT-2, ISG-54 K, IFI54, p54, Interferon-induced protein 54, ISG-54K, ISG54, G10P2 |
| Target Sequences: | M14660 AAA59191.1 P09913 |
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Products
Antibodies
(30)
Type
Primary
(30)
Target
ISG54 / IFIT2
(30)
Reactivity
Human
(30)
Mouse
(1)
Rat
(1)
Chimpanzee
(3)
Gibbon
(3)
Monkey
(3)
Orangutan
(3)
Application
IHC
(4)
IHC-P
(2)
WB
(26)
ELISA
(13)
IF
(3)
Peptide-ELISA
(1)
Host
rabbit
(29)
mouse
(1)
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IgG
(26)
Clonality
polyclonal pc
(30)
Format
APC Conjugated
(2)
Azide-free
(1)
Biotin Conjugated
(4)
FITC Conjugated
(4)
HRP Conjugated
(4)
PE Conjugated
(2)
Unconjugated
(14)
Epitope
aa307-335
(7)
N-Terminus
(4)
aa100-321
(1)
aa320-370
(1)
Publications
No
(30)
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa100-321) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
ISG54 / IFIT2 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa320-370) Antibody
Mouse, Human
WB
Unconjugated
0.1 mg/$386
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
ISG54 / IFIT2 Rabbit anti-Human Polyclonal (aa307-335) Antibody
Human
WB
Unconjugated
400 µl/$393
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ISG54 / IFIT2 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
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product results
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