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ISCU

iron-sulfur cluster assembly enzyme

Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. A pseudogene of this gene is present on chromosome 1. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: iron-sulfur cluster assembly enzyme
Synonyms: ISCU, ISU2, NifU-like protein, NIFUN, HML, NIFU, HnifU
Target Sequences: AK022758 AAG37428.1 Q9H1K1

☰ Filters
Antibodies (27)
Proteins (10)
Over-Expression Lysate (4)
Primary (27)
Recombinant (6)
ISCU (37)
Human (26)
Mouse (13)
Rat (6)
Bat (3)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (3)
Rabbit (3)
Xenopus (3)
IHC (8)
IHC-P (3)
WB (21)
ELISA (16)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (22)
mouse (5)
Product Group
IHCPlus (1)
IgG (16)
IgG1 (4)
IgG1,k (1)
monoclonal mc (5)
polyclonal pc (22)
3D12-1D10 (1)
OTI4F5 (2)
OTI8H2 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
Carrier-free (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (16)
aa138-167 (7)
N-Terminus (4)
aa3-148 (1)
No (37)
GST (1)
GST, N-terminus (3)
His (1)
Myc-DDK (Flag) (5)
Human (8)
293T Cells (2)
E. coli (3)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (4)
ISCU Antibody - ISCU Antibody western blot of WiDr cell line lysates (35 ug/lane). The ISCU antibody detected the ISCU protein (arrow).
Select
ISCU Rabbit anti-Human Polyclonal (aa138-167) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
Select
ISCU Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
ISCU Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
ISCU Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ISCU Antibody - ISCU antibody Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ISCU Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat
WB
Unconjugated
100 µl/$424
ISCU Antibody - ISCU antibody Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ISCU Rabbit anti-Rat Polyclonal (N-Terminus) (FITC) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Hamster, Horse, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
ISCU Antibody - Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
ISCU Rabbit anti-Human Polyclonal (aa3-148) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ISCU Antibody - IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-ISCU mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
ISCU Mouse anti-Human Monoclonal (OTI4F5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
ISCU Antibody - IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-ISCU mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
ISCU Mouse anti-Human Monoclonal (Carrier-free) (OTI4F5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ISCU Antibody - Immunohistochemistry of paraffin-embedded human endometrial cancer at dilution 1:100
Select
ISCU Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
ISCU Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ISCU Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using ISCU Polyclonal Antibody at dilution of 1:45(×200)
Select
ISCU Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
ISCU Mouse anti-Human Monoclonal (3D12-1D10) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
ISCU Rabbit anti-Human Polyclonal (aa138-167) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
ISCU Rabbit anti-Human Polyclonal (aa138-167) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ISCU Rabbit anti-Human Polyclonal (aa138-167) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ISCU Rabbit anti-Human Polyclonal (aa138-167) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ISCU Rabbit anti-Human Polyclonal (aa138-167) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
ISCU Rabbit anti-Human Polyclonal (aa138-167) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ISCU Antibody - Western blot analysis of Mouse lung tissue lysate  using ISCU Polyclonal Antibody at dilution of 1:400
Select
ISCU Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ISCU Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ISCU (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ISCU.
Select
ISCU Mouse anti-Human Monoclonal (OTI8H2) Antibody
Human
WB
Unconjugated
100 µl/$434
ISCU Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ISCU (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ISCU.
Select
ISCU Mouse anti-Human Monoclonal (Carrier-free) (OTI8H2) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
Select
ISCU Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
ISCU Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ISCU Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
ISCU Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 37 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).