Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
IRAK3 / IRAKM / IRAK-M is a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
Gene Name: | interleukin-1 receptor-associated kinase 3 |
Family/Subfamily: | Protein Kinase , IRAK(Pelle) |
Synonyms: | IRAK3, ASRT5, IRAK M, IRAK-3, IL1RAK M, IRAK-M, IRAKM |
Target Sequences: | NM_007199 NP_009130.2 Q9Y616 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.