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IRAK2 / IRAK-2

interleukin-1 receptor-associated kinase 2

IRAK2, an IRAK type protein kinase, is a signal transducer for the immune response interleukin-1 receptor (IL-1R) signaling cascade. IRAK2 also has been associated with signaling cell death, potentially via the Fas-associated death domain protein/caspase-8 apoptotic pathway. Dominant negative forms of IRAK2 attenuate IL-1R-mediated NF-kappa B activation, suggesting that IRAK-2 may serve as a therapeutic target for inhibiting IL-1-induced inflammation.

Gene Name:	interleukin-1 receptor-associated kinase 2
Family/Subfamily:	Protein Kinase , IRAK(Pelle)
Synonyms:	IRAK2, Il1rak2, IRAK-2
Target Sequences:	NM_001570 NP_001561.3 O43187

Human IRAK2 / IRAK-2 (Sandwich ELISA) ELISA Kit - LS-F38986

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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