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IP6K2

inositol hexakisphosphate kinase 2

IP6K2 is a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: inositol hexakisphosphate kinase 2
Family/Subfamily: Non-protein Kinase , IHPK
Synonyms: IP6K2, IHPK2, Phosphate uptake stimulator, InsP6 kinase 2, Insp6k2, P(i)-uptake stimulator, Pi uptake stimulator, PIUS
Target Sequences: NM_016291 NP_057375.2 Q9UHH9

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Products
Antibodies (26)
Primary (26)
IP6K2 (26)
Human (25)
Mouse (9)
Rat (8)
IHC (10)
IHC-P (3)
WB (24)
ELISA (14)
ICC (1)
IF (9)
IP (1)
Peptide-ELISA (4)
rabbit (16)
mouse (10)
Product Group
IHCPlus (1)
IgG (14)
IgG2a (2)
IgG2a,k (6)
IgG2b (1)
monoclonal mc (9)
polyclonal pc (17)
4F10 (1)
OTI1F12 (2)
APC Conjugated (1)
Biotin Conjugated (1)
Carrier-free (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (21)
aa1-250 (2)
130-210 aa, Internal (1)
Internal (1)
Leu188 (1)
aa1-71 (1)
aa139-188 (1)
aa161-210 (1)
aa226-258 (1)
No (26)
IP6K2 Antibody - Human, Small Intestine: Formalin-Fixed Paraffin-Embedded (FFPE)
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IP6K2 Rabbit anti-Human Polyclonal (aa161-210) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
IP6K2 Antibody - Immunohistochemical analysis of IP6K2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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IP6K2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351
IP6K2 Antibody - Western blot of IP6K2 antibody
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IP6K2 Rabbit anti-Human Polyclonal (130-210 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
IP6K2 Antibody - Immunohistochemistry of paraffin-embedded human rectum tissue at dilution 1:100
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IP6K2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
IP6K2 Antibody - Western blot of IP6K2 (L188) pAb in extracts from A549 cells.
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IP6K2 Rabbit anti-Human Polyclonal (Leu188) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
IP6K2 Antibody - Immunofluorescence analysis of A549 cells.
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IP6K2 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
IP6K2 Antibody - Staining HuvEc cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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IP6K2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$282; 200 µl/$350
IP6K2 Antibody - Peptide - + Immunofluorescence analysis of COS-7 cells, using IP6K2 antibody.
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IP6K2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
IP6K2 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using IP6K2 Polyclonal Antibody at dilution of 1:220(×200)
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IP6K2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IP6K2 Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using IP6K2 Polyclonal Antibody at dilution of 1:45(×200)
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IP6K2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IP6K2 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using IP6K2 Polyclonal Antibody at dilution of 1:50(×200)
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IP6K2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IP6K2 Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using IP6K2 Polyclonal Antibody at dilution of 1:140(×200)
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IP6K2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
IP6K2 Mouse anti-Human Monoclonal (aa1-71) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Select
IP6K2 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
IP6K2 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
IP6K2 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
IP6K2 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
Select
IP6K2 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
Select
IP6K2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
Select
IP6K2 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
IP6K2 Antibody - Anti-IP6K2 Antibody (Center)at 1:2000 dilution + mouse brain lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 49 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
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IP6K2 Rabbit anti-Human Polyclonal (aa226-258) Antibody
Mouse
Peptide-ELISA, WB
Unconjugated
200 µl/$393
IP6K2 Antibody - Western blot analysis of the lysates from K562 cells using IP6K2 antibody.
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IP6K2 Rabbit anti-Human Polyclonal (aa139-188) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
IP6K2 Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
20 µl/$275; 100 µl/$389
IP6K2 Antibody - Effect of ?-irradiation and IFN-ß on IP6K2 protein levels. (a) NIH-OVCAR-3 cells growing at 75% confluence were trypsinized, suspended in 1 ml PBS, and subject to 0, 1 (white bars) or Gy (gray bars) irradiation and replated in complete medium. At 8 and 16 h after plating, cells were harvested, lysed and subject to Western blot analysis using monoclonal anti-IP6K2 antibodies. To control for loading, blots were probed with anti-actin antibodies; bands were digitized and quantified. IP6K2 signal intensity was normalized to actin, then expressed as fold induction, with unirradiated cells representing a protein level of 1. Purified rIP6K2 was included as a positive control (lane 1). Numbers to right of blots indicate MW markers. Only relevant portion of the blots are shown. (b) NIH-OVCAR-3 cells were grown in the presence of 200 U/ml IFN-ß for 0-48  h and then subject to Western blot analysis and quantified as above.
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IP6K2 Mouse anti-Human Monoclonal (4F10) Antibody
Human
WB
Unconjugated
100 µg/$484
IP6K2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY IP6K2. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IP6K2. (1:500)
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IP6K2 Mouse anti-Human Monoclonal (aa1-250) (Carrier-free) (OTI1F12) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
Viewing 1-25 of 26 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).