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LPAM-1 (integrin alpha 4 beta 7) mediates lymphocyte attachment within the extracellular matrix (ECM) by adhering to the connecting segment (CS)-1 site of fibronectin (FN). It is upregulated in atherosclerotic lesions and is involved in atherosclerosis progression.
Target Name: | Integrin Alpha4 Beta7 (ITGA4/ITGB7) |
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