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Inositol 5-phosphatase which acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Hydrolyzes phosphatidylinositol 4,5-bisphosphate most effectively. Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation.
Gene Name: | inositol polyphosphate-5-phosphatase F |
Synonyms: | INPP5F, HSAC2, KIAA0966, MSTP007, MSTPO47, SAC2 |
Target Sequences: | NM_014937 NP_055752.1 Q9Y2H2 |
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