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Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Gene Name: | inhibin, beta C |
Family/Subfamily: | TGF beta , not assigned-TGF beta |
Synonyms: | INHBC, Activin beta-C chain, IHBC, Inhibin, beta C, Inhibin beta c chain |
Target Sequences: | NM_005538 NP_005529.1 P55103 |
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